您的位置：首页 > 产品中心 > Sulfo-EGS (ethylene glycol bis(sulfosuccinimidyl succinate))
Sulfo-EGS (ethylene glycol bis(sulfosuccinimidyl succinate))
结构式
基本信息
| Empirical Formula【经验(实验)分子式】 | C18H18O18N2Na2S2 |
| Molecular weight | 660.45 |
| MDL number | MFCD00054988 |
| PubChem Substance ID【PubChem化学物质编号】 | 329768789 |
| NACRES | NA.22 |
| General description【一般描述】 | EGS is a water-insoluble, homobifunctional N-hydroxysuccinimide ester (NHS ester) and Sulfo-EGS is its water-soluble analog. The spacer arm contains two cleavable ester sites that may be broken with hydroxylamine, which yields two fragments with terminal amide bonds and the release of ethylene glycol. These reagents are often used for conjugating radiolabeled ligands to cell surface receptors. The water insoluble reagent EGS does not possess a charged group, is lipophilic and, therefore, membrane-permeable and useful for intracellular and intramembrane protein conjugation. EGS is first dissolved in DMSO or DMF and added to the aqueous reaction mixture at a final solvent concentration of 10-20%, to minimize detrimental affects to the protein. |
| Features and Benefits【特点和优势】 |
|
| Caution【注意】 | This product is sensitive to moisture. The vial is packaged in a resealable bag with a desiccant to reduce exposure to moisture. After cold storage, equilibrate the vial to room temperature before opening to reduce condensation inside the vial. Make fresh solutions. Storage of stock solutions is not recommended. After use, return the vial to the resealable bag. Close the bag and store the product at the recommended temperature. |
产品性质
| form【形式】 | powder |
| Quality Level【质量水平】 | 100 |
| mol wt【分子量】 | 660.45 |
| reaction suitability | reagent type: cross-linking reagent |
| storage condition【储存条件】 | desiccated |
| solubility【溶解性】 | water: soluble |
| shipped in【运输】 | ambient |
| storage temp.【储存温度】 | −20℃ |
| InChI | 1S/C18H20N2O18S2.2Na/c21-11-7-9(39(29,30)31)17(27)19(11)37-15(25)3-1-13(23)35-5-6-36-14(24)2-4-16(26)38-20-12(22)8-10(18(20)28)40(32,33)34;;/h9-10H,1-8H2,(H,29,30,31)(H,32,33,34);;/q;2*+1/p-2 |
| InChI key | IYBKWXQWKPSYDT-UHFFFAOYSA-L |
安全信息
| Pictograms【象形图】 | GHS07 |
| Signal word【警示用语：】 | Warning |
| Hazard Statements | H315 - H319 - H335 |
| Precautionary Statements | P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338 |
| Hazard Classifications【危险分类】 | Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3 |
| Target Organs【靶器官】 | Respiratory system |
| Storage Class Code【储存分类代码】 | 11 - Combustible Solids |
| WGK | WGK 3 |
