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TAK-715
产品别名
303162-79-0
TAK-715
N-(4-(2-Ethyl-4-(3-methylphenyl)-1,3-thiazol-5-yl)-2-pyridyl)benzamide
结构式
基本信息
| Empirical Formula【经验(实验)分子式】 | C24H21N3OS |
| Molecular weight | 399.51 |
| MDL number | MFCD17012805 |
| PubChem Substance ID【PubChem化学物质编号】 | 329825362 |
| NACRES | NA.77 |
| Biochem/physiol Actions【生化/生理作用】 | TAK-715 is a potent p38 inhibitor that also inhibits CKId/e (casein kinase Id/e), known activator of Wnt/β-catenin signaling. |
| Features and Benefits【特点和优势】 | This compound is featured on the MAPKs page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here. |
产品性质
| Quality Level【质量水平】 | 100 |
| Assay【测定】 | ≥98% (HPLC) |
| form【形式】 | powder |
| color【颜色】 | faintly yellow to dark yellow |
| solubility【溶解性】 | DMSO: >15 mg/mL |
| storage temp.【储存温度】 | 2-8℃ |
| SMILES string | CCc1nc(-c2cccc(C)c2)c(s1)-c3ccnc(NC(=O)c4ccccc4)c3 |
| InChI | 1S/C24H21N3OS/c1-3-21-27-22(18-11-7-8-16(2)14-18)23(29-21)19-12-13-25-20(15-19)26-24(28)17-9-5-4-6-10-17/h4-15H,3H2,1-2H3,(H,25,26,28) |
| InChI key | HEKAIDKUDLCBRU-UHFFFAOYSA-N |
| Gene Information | human ... MAPK14(1432) |
| packaging【包装】 | 5, 25 mg in glass bottle |
安全信息
| Pictograms【象形图】 | GHS07 |
| Signal word【警示用语：】 | Warning |
| Hazard Statements | H302 - H319 |
| Precautionary Statements | P301 + P312 + P330 - P305 + P351 + P338 |
| Hazard Classifications【危险分类】 | Acute Tox. 4 Oral - Eye Irrit. 2 |
| Storage Class Code【储存分类代码】 | 11 - Combustible Solids |
| WGK | WGK 3 |
