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Tipiracil hydrochloride
产品价格查看更多规格...
| 产品编号 | 包装单位 | 单价(元) | 国内现货 | 国外库存 | 询价单 |
| 3252761 | 10 MG | 1690 | |||
| 3252761 | 50 MG | 6190 |
产品别名
183204-72-0
Tipiracil hydrochloride
5-Chloro-6-[(2-imino-1-pyrrolidinyl)methyl]-2,4(1H,3H)-pyrimidinedione hydrochloride
TPI hydrochloride
结构式
基本信息
| Empirical Formula【经验(实验)分子式】 | C9H11ClN4O2 · HCl |
| Molecular weight | 279.12 |
| MDL number | MFCD01571384 |
| PubChem Substance ID【PubChem化学物质编号】 | 329825960 |
| NACRES | NA.77 |
| Biochem/physiol Actions【生化/生理作用】 | Tipiracil is an inhibitor of thymidine phosphorylase. Tipiracil is used in combination with trifluridine as TAS-102 for the treatment of refractory metastatic colorectal cancer. Tipiracil increases the bioavailability of trifluridine by blocking the enzyme that would otherwise protect the tumors by metabolizing trifluridine. |
产品性质
| Quality Level【质量水平】 | 100 |
| Assay【测定】 | ≥98% (HPLC) |
| form【形式】 | powder |
| storage condition【储存条件】 | desiccated |
| color【颜色】 | white to beige |
| solubility【溶解性】 | H2O: 5 mg/mL, clear (warmed) |
| storage temp.【储存温度】 | 2-8℃ |
| SMILES string | [H]Cl.ClC1=C(CN2C(CCC2)=N)NC(NC1=O)=O |
| InChI | 1S/C9H11ClN4O2.ClH/c10-7-5(12-9(16)13-8(7)15)4-14-3-1-2-6(14)11;/h11H,1-4H2,(H2,12,13,15,16);1H |
| InChI key | KGHYQYACJRXCAT-UHFFFAOYSA-N |
| Gene Information | human ... TYMP(1890) |
| packaging【包装】 | 10, 50 mg in glass bottle |
安全信息
| Storage Class Code【储存分类代码】 | 11 - Combustible Solids |
| WGK | WGK 3 |
