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Tolfenamic Acid
产品编号:3253448
规格:NSAID
CAS NO:13710-19-5
包装规格:5 G
产品类别:进口试剂
品牌:Sigma-Aldrich
优惠价:立即咨询
产品编号包装单位单价(元)国内现货国外库存询价单
32534485 G1110
产品别名

13710-19-5

托芬那酸

Tolfenamic Acid

2 (3-Chloro-2-methylanilino)benzoic acid

2-([3-Chloro-2-methylphenyl]amino)benzoic acid

2-(3-氯-2-甲基苯胺)苯甲酸

2-([3-氯-2-甲苯基]氨基)苯甲酸

结构式
基本信息
Empirical Formula【经验(实验)分子式】
C14H12ClNO2
Molecular weight
261.70
EC number【EC 号】
237-264-3
MDL number
MFCD00133865
PubChem Substance ID【PubChem化学物质编号】
24899896
NACRES
NA.77
General description【一般描述】
Tolfenamic acid is a fenamate and is made up of a monocarboxylate diphenylamine nucleus.
Application【应用】
Tolfenamic acid has been used in Arabidopsis bud assay for activity comparison with quinazolinedione derivatives (QADD) based compounds.
Biochem/physiol Actions【生化/生理作用】
Tolfenamic acid is involved in the inhibition of prostaglandin synthesis. It also plays a role in apoptosis of head and neck cancer cells.
Non-steroidal anti-inflammatory agent. Interferes with synthesis of β-amyloid precursor protein, and thus Aβ peptides, by promoting degradation of an essential transcription factor.
产品性质
Quality Level【质量水平】
200
Assay【测定】
≥98% (TLC)
form【形式】
powder
solubility【溶解性】
ethanol: 50 mg/mL, clear, greenish-yellow
SMILES string
Cc1c(Cl)cccc1Nc2ccccc2C(O)=O
InChI
1S/C14H12ClNO2/c1-9-11(15)6-4-8-12(9)16-13-7-3-2-5-10(13)14(17)18/h2-8,16H,1H3,(H,17,18)
InChI key
YEZNLOUZAIOMLT-UHFFFAOYSA-N
packaging【包装】
5 g in glass bottle
安全信息
Pictograms【象形图】
GHS06
Signal word【警示用语:】
Danger
Hazard Statements
H301
Precautionary Statements
P301 + P310
Hazard Classifications【危险分类】
Acute Tox. 3 Oral
Storage Class Code【储存分类代码】
6.1D - Non-combustible, acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects
WGK
WGK 3
Personal Protective Equipment【个人防护装备】
dust mask type N95 (US), Eyeshields, Faceshields, Gloves
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