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Treosulfan
产品别名
299-75-2
Treosulfan
Treosulphan
NSC 39069
Threosulphan
(2S,3S)-Threitol 1,4-bismethanesulfonate
L-Threitol 1,4-bis(methanesulfonate)
(2S,3S)-Butanetetraol 1,4-dimesylate
基本信息
| Empirical Formula【经验(实验)分子式】 | C6H14O8S2 |
| Molecular weight | 278.30 |
| NACRES | NA.77 |
| Biochem/physiol Actions【生化/生理作用】 | Treosulfan/l-threitol-1,4-bis-methanesulfonate; dihydroxybusulfan; NSC 39069. It is a prodrug of a bifunctional alkylating cytotoxic agent. Treosulfan can be activated non-enzymatically to two active epoxides. It is used to treat ovarian cancer. Treosulfan is bifunctional alkylating agent. Treosulfan is a biofunctional alkylating agent. |
产品性质
| Quality Level【质量水平】 | 100 |
| Assay【测定】 | ≥98% (HPLC) |
| form【形式】 | powder |
| optical activity【旋光性】 | [α]/D -4.9 to -5.9°, c = 1 in acetone |
| color【颜色】 | white to beige |
| solubility【溶解性】 | H2O: 5 mg/mL, clear |
| storage temp.【储存温度】 | −20℃ |
| InChI | 1S/C6H14O8S2/c1-15(9,10)13-3-5(7)6(8)4-14-16(2,11)12/h5-8H,3-4H2,1-2H3 |
| InChI key | YCPOZVAOBBQLRI-UHFFFAOYSA-N |
| packaging【包装】 | 5, 25 mg in glass bottle |
安全信息
| Pictograms【象形图】 | GHS08 |
| Signal word【警示用语：】 | Danger |
| Hazard Statements | H340 - H350 - H361f |
| Precautionary Statements | P201 - P202 - P280 - P308 + P313 - P405 - P501 |
| Hazard Classifications【危险分类】 | Carc. 1A - Muta. 1B - Repr. 2 |
| Storage Class Code【储存分类代码】 | 6.1C - Combustible, acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects |
| WGK | WGK 3 |
