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Tyrphostin AG 825
产品价格查看更多规格...
| 产品编号 | 包装单位 | 单价(元) | 国内现货 | 国外库存 | 询价单 |
| 3257627 | 2 MG | 1660 |
产品别名
149092-50-2
Tyrphostin AG 825
Tyrphostin C15
5-[(Benzothiazol-2-yl)thiomethyl]-4-hydroxy-3-methoxybenzylidenecyanoacetamide
结构式
基本信息
| Empirical Formula【经验(实验)分子式】 | C19H15N3O3S2 |
| Molecular weight | 397.47 |
| MDL number | MFCD01074971 |
| PubChem Substance ID【PubChem化学物质编号】 | 329826823 |
| NACRES | NA.77 |
| Application【应用】 | Tyrphostin AG 825 has been used to study its effects on iodide uptake in EMT6 cells1. |
| Biochem/physiol Actions【生化/生理作用】 | Tyrphostin AG 825 has been used in combination with hypericin-mediated photodynamic therapy (HY-PDT) for evaluating its therapeutic effects in HER2 overexpressing human breast cancer cells. This study reported that AG 825 combination increased the induction of cell death, HER2 degradation and inhibited colony formation in cancer cells2. EGF receptor tyrosine kinase inhibitor, inactive against IGF-1 Receptor. |
| Features and Benefits【特点和优势】 | This compound is a featured product for Kinase Phosphatase Biology research. Click here to discover more featured Kinase Phosphatase Biology products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm. |
| Preparation Note【制备说明】 | Tyrphostin AG 825 is soluble in DMSO and methanol. |
产品性质
| Quality Level【质量水平】 | 200 |
| Assay【测定】 | ≥92.5% |
| form【形式】 | powder |
| solubility【溶解性】 | DMSO: soluble methanol: soluble |
| storage temp.【储存温度】 | −20℃ |
| SMILES string | COc1cc(cc(CSc2nc3ccccc3s2)c1O)\C=C(/C#N)C(N)=O |
| InChI | 1S/C19H15N3O3S2/c1-25-15-8-11(6-12(9-20)18(21)24)7-13(17(15)23)10-26-19-22-14-4-2-3-5-16(14)27-19/h2-8,23H,10H2,1H3,(H2,21,24)/b12-6+ |
| InChI key | KXDONFLNGBQLTN-WUXMJOGZSA-N |
安全信息
| Storage Class Code【储存分类代码】 | 13 - Non Combustible Solids |
| WGK | WGK 3 |
| Personal Protective Equipment【个人防护装备】 | Eyeshields, Gloves, type N95 (US) |
