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U-74389G

产品编号:3257661
CAS NO:153190-29-5
包装规格:100 MG
产品类别:进口试剂
品牌:Sigma-Aldrich
优惠价:立即咨询
产品编号包装单位单价(元)国内现货国外库存询价单
3257661100 MG3350
产品别名

153190-29-5

U-74389G

21-[4-(2,6-Di-1-pyrrolidinyl-4-pyrimidinyl)-1-piperazinyl]pregna-1,4,9[11]-triene-3,20-dione maleate salt

结构式
基本信息
Empirical Formula【经验(实验)分子式】
C37H50N6O2 · C4H4O4
Molecular weight
726.90
MDL number
MFCD01074991
PubChem Substance ID【PubChem化学物质编号】
24278768
NACRES
NA.77
Application【应用】
U-74389G has been shown to significantly decrease the level of ethanol-induced gastric mucosal necrosis in portal hypertensive (PHT) rats. Furthermore, U-74389G has been widely used in animal models of ischemic injury and hypertension.
Biochem/physiol Actions【生化/生理作用】
Free radical lipid peroxidation inhibitor in cultured brain cells, monocytic THP1 cells, and LLC-PK1 cell layers.
Preparation Note【制备说明】
U-74389G is soluble in ethanol at 20 mg/ml and yields a clear, light yellow solution.
产品性质
solubility【溶解性】
ethanol: soluble 20 mg/mL, clear, light yellow
storage temp.【储存温度】
−20℃
SMILES string
OC(=O)\C=C/C(O)=O.[H][C@@]12CCC3=CC(=O)C=C[C@]3(C)C1=CC[C@]4(C)[C@H](CC[C@@]24[H])C(=O)CN5CCN(CC5)c6cc(nc(n6)N7CCCC7)N8CCCC8
InChI
1S/C37H50N6O2.C4H4O4/c1-36-13-11-27(44)23-26(36)7-8-28-29-9-10-31(37(29,2)14-12-30(28)36)32(45)25-40-19-21-42(22-20-40)34-24-33(41-15-3-4-16-41)38-35(39-34)43-17-5-6-18-43;5-3(6)1-2-4(7)8/h11-13,23-24,28-29,31H,3-10,14-22,25H2,1-2H3;1-2H,(H,5,6)(H,7,8)/b;2-1-/t28-,29-,31+,36-,37-;/m0./s1
InChI key
ABCSSKWSUJMJCP-WQDFMEOSSA-N
packaging【包装】
100 mg in glass insert
安全信息
Storage Class Code【储存分类代码】
11 - Combustible Solids
WGK
WGK 3
Personal Protective Equipment【个人防护装备】
Eyeshields, Gloves, type N95 (US)
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