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VU0361737
产品别名
1161205-04-4
VU0361737
ML128
N-(4-Chloro-3-methoxyphenyl)-2-pyridinecarboxamide
CID-44191096
结构式
基本信息
| Empirical Formula【经验(实验)分子式】 | C13H11ClN2O2 |
| Molecular weight | 262.69 |
| MDL number | MFCD16618402 |
| PubChem Substance ID【PubChem化学物质编号】 | 329825444 |
| NACRES | NA.77 |
| Biochem/physiol Actions【生化/生理作用】 | VU0361737 is an mGluR4-specific positive allosteric modulator (PAM) with greater than 50 fold selectivity over other mGluR subtypes. The EC50 values for human and rat mGlu4 are 240 and 110 nM, respectively, compared to greater than 10 mM for all other mGluRs. |
| Features and Benefits【特点和优势】 | This compound is featured on the Glutamate Receptors (G Protein Family) page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here. |
产品性质
| Assay【测定】 | ≥98% (HPLC) |
| form【形式】 | film |
| color【颜色】 | white |
| solubility【溶解性】 | DMSO: 15 mg/mL (clear solution) |
| storage temp.【储存温度】 | 2-8℃ |
| SMILES string | COc1cc(NC(=O)c2ccccn2)ccc1Cl |
| InChI | 1S/C13H11ClN2O2/c1-18-12-8-9(5-6-10(12)14)16-13(17)11-4-2-3-7-15-11/h2-8H,1H3,(H,16,17) |
| InChI key | ARYUXFNGXHNNDM-UHFFFAOYSA-N |
| packaging【包装】 | 5, 25 mg in glass bottle |
安全信息
| Pictograms【象形图】 | GHS07 |
| Signal word【警示用语：】 | Warning |
| Hazard Statements | H302 - H319 |
| Precautionary Statements | P305 + P351 + P338 |
| Hazard Classifications【危险分类】 | Acute Tox. 4 Oral - Eye Irrit. 2 |
| Storage Class Code【储存分类代码】 | 13 - Non Combustible Solids |
| WGK | WGK 3 |
