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WAY-208466 二盐酸盐
WAY-208466 dihydrochloride
产品别名
1207064-61-6
WAY-208466 二盐酸盐
WAY-208466 dihydrochloride
WAY208466 dihydrochloride
WAY 208466 dihydrochloride
3-[(3-Fluorophenyl)sulfonyl]-N,N-dimethyl-1H-pyrrolo[2,3-b]pyridine-1-ethanamine hydrochloride (1:2)
结构式
基本信息
| Empirical Formula【经验(实验)分子式】 | C17H18FN3O2S · 2HCl |
| Molecular weight | 420.33 |
| MDL number | MFCD28384460 |
| PubChem Substance ID【PubChem化学物质编号】 | 329823827 |
| NACRES | NA.77 |
| Biochem/physiol Actions【生化/生理作用】 | WAY-208466 is a high affinity (Ki = 4.8 nM) 5-HT6 receptor agonist. In HeLa cells expressing cloned human 5-HT6, the compound induced cAMP production (EC50 = 7.3 nM; Emax = 100%). WAY-208466 increases cortical GABA levels and exhibits anxiolytic activity in rat studies. |
| Other Notes【其他说明】 | This compound was developed by Pfizer for Neuroscience research. To learn more about Sigma′s partnership with Pfizer and view other authentic, high-quality Pfizer compounds, visit sigma.com/bsm-pfizer. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here. |
| Legal Information【法律信息】 | Sold for research purposes under agreement from Pfizer Inc. Pfizer is a registered trademark of Pfizer, Inc. |
产品性质
| Quality Level【质量水平】 | 100 |
| Assay【测定】 | ≥98% (HPLC) |
| form【形式】 | powder |
| manufacturer/tradename | Pfizer® |
| color【颜色】 | white to beige |
| solubility【溶解性】 | H2O: 5 mg/mL, clear (warmed) |
| originator【创始人】 | Pfizer |
| storage temp.【储存温度】 | room temp |
| SMILES string | CN(C)CCN1C=C(S(C2=CC=CC(F)=C2)(=O)=O)C3=CC=CN=C31 |
| InChI | 1S/C17H18FN3O2S/c1-20(2)9-10-21-12-16(15-7-4-8-19-17(15)21)24(22,23)14-6-3-5-13(18)11-14/h3-8,11-12H,9-10H2,1-2H3 |
| InChI key | SFSFIDVAEMDPIP-UHFFFAOYSA-N |
| packaging【包装】 | 5, 25 mg in glass bottle |
安全信息
| Pictograms【象形图】 | GHS07 |
| Signal word【警示用语：】 | Warning |
| Hazard Statements | H315 - H319 - H335 |
| Precautionary Statements | P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338 |
| Hazard Classifications【危险分类】 | Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3 |
| Target Organs【靶器官】 | Respiratory system |
| Storage Class Code【储存分类代码】 | 11 - Combustible Solids |
| WGK | WGK 3 |
