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Y16
产品别名
429653-73-6
Y16
4-[[3-[(3-Methylphenyl)methoxy]phenyl]methylene]-1-phenyl-3,5-pyrazolidinedione
基本信息
| Empirical Formula【经验(实验)分子式】 | C24H20N2O3 |
| Molecular weight | 384.43 |
| NACRES | NA.77 |
| Biochem/physiol Actions【生化/生理作用】 | Y16 blocks the binding of LARG, a DBL-family Rho guanine nucleotide exchange factor, with Rho (Kd = 80 nM). Y16 specifically inhibits LARG catalyzed activation of RhoA and RhoA signaling pathways. Y16 blocks the growth and migration of MCF7 breast cancer cells. |
| Features and Benefits【特点和优势】 | This compound is a featured product for Cyclic Nucleotide research. Click here to discover more featured Cyclic Nucleotide products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm. This compound is featured on the GTP Binding Proteins (Low Molecular Weight) page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here. |
| Other Notes【其他说明】 | Product is a racemic mixture of E/Z isomers. |
产品性质
| Quality Level【质量水平】 | 100 |
| Assay【测定】 | ≥98% (HPLC) |
| form【形式】 | powder |
| color【颜色】 | , faint yellow to dark orange |
| solubility【溶解性】 | DMSO: 5 mg/mL, clear (warmed) |
| storage temp.【储存温度】 | 2-8℃ |
| packaging【包装】 | 5, 25 mg in glass bottle |
安全信息
| Storage Class Code【储存分类代码】 | 11 - Combustible Solids |
| WGK | WGK 3 |
