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Z-Ile-Glu(O-ME)-Thr-Asp(O-Me) fluoromethyl ketone
产品别名
220760-26-9
Z-Ile-Glu(O-ME)-Thr-Asp(O-Me) fluoromethyl ketone
Z-IETD-FMK
结构式
基本信息
| Empirical Formula【经验(实验)分子式】 | C30H43FN4O11 |
| Molecular weight | 654.68 |
| MDL number | MFCD01861686 |
| PubChem Substance ID【PubChem化学物质编号】 | 329774744 |
| NACRES | NA.77 |
| Amino Acid Sequence | Z-Ile-Glu-OMe-Thr-Asp-OMe-FMK |
| Application【应用】 | Z-Ile-Glu(O-ME)-Thr-Asp(O-Me) fluoromethyl ketone (Z-IETD-FMK) has been used as a caspase-8 inhibitor:
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| Biochem/physiol Actions【生化/生理作用】 | Z-Ile-Glu(O-ME)-Thr-Asp(O-Me) fluoromethyl ketone (Z-IETD-FMK) is an irreversible and cell-permeable caspase-8 inhibitor. |
| Features and Benefits【特点和优势】 | This compound is featured on the Caspases page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here. |
产品性质
| Quality Level【质量水平】 | 200 |
| biological source【生物来源】 | synthetic (organic) |
| Assay【测定】 | ≥90% (TLC) |
| form【形式】 | powder |
| solubility【溶解性】 | methanol: 10 mg/mL DMSO: 20 mM, clear, colorless to light yellow |
| shipped in【运输】 | dry ice |
| storage temp.【储存温度】 | −20℃ |
| SMILES string | CC[C@H](C)[C@H](NC(=O)OCc1ccccc1)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](C(C)O)C(=O)N[C@@H](CC(O)=O)C(=O)CF |
| InChI | 1S/C28H39FN4O11/c1-4-15(2)23(33-28(43)44-14-17-8-6-5-7-9-17)26(41)30-18(10-11-21(36)37)25(40)32-24(16(3)34)27(42)31-19(12-22(38)39)20(35)13-29/h5-9,15-16,18-19,23-24,34H,4,10-14H2,1-3H3,(H,30,41)(H,31,42)(H,32,40)(H,33,43)(H,36,37)(H,38,39)/t15-,16+,18-,19-,23-,24-/m0/s1 |
| InChI key | CTXDBLYOEUERAT-VUVYEONESA-N |
安全信息
| Storage Class Code【储存分类代码】 | 13 - Non Combustible Solids |
| WGK | WGK 3 |
| Personal Protective Equipment【个人防护装备】 | Eyeshields, Gloves, type N95 (US) |
