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Z-Leu-Leu-Glu-7-amido-4-methylcoumarin
产品别名
Z-Leu-Leu-Glu-7-amido-4-methylcoumarin
Z-LLE-AMC
Cbz-Leu-Leu-Glu-AMC
结构式
基本信息
| Empirical Formula【经验(实验)分子式】 | C35H44N4O9 |
| Molecular weight | 664.75 |
| MDL number | MFCD01074989 |
| PubChem Substance ID【PubChem化学物质编号】 | 329774798 |
| Amino Acid Sequence | Z-Leu-Leu-Glu-AMC |
| General description【一般描述】 | Z-Leu-Leu-Glu-7-amido-4-methylcoumarin is a fluoropeptide. It acts as a substrate for caspase-like activity. |
| Application【应用】 | Z-Leu-Leu-Glu-7-amido-4-methylcoumarin has been used as a fluorogenic substrate for peptidyl glutamyl peptide hydrolase (PGPH) in rat soleus muscle, neonatal cardiomyocytes and rat brain samples. |
| Biochem/physiol Actions【生化/生理作用】 | Fluorogenic substrate for the measurement of the peptidylglutamyl-peptide hydrolyzing activity of the 20S proteasome. |
产品性质
| Quality Level【质量水平】 | 200 |
| Assay【测定】 | ≥95% |
| form【形式】 | solid |
| solubility【溶解性】 | DMSO: soluble |
| storage temp.【储存温度】 | −20℃ |
| SMILES string | CC(C)C[C@H](NC(=O)OCc1ccccc1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCC(O)=O)C(=O)Nc2ccc3C(C)=CC(=O)Oc3c2 |
| InChI | 1S/C35H44N4O9/c1-20(2)15-27(38-34(45)28(16-21(3)4)39-35(46)47-19-23-9-7-6-8-10-23)33(44)37-26(13-14-30(40)41)32(43)36-24-11-12-25-22(5)17-31(42)48-29(25)18-24/h6-12,17-18,20-21,26-28H,13-16,19H2,1-5H3,(H,36,43)(H,37,44)(H,38,45)(H,39,46)(H,40,41)/t26-,27-,28-/m0/s1 |
| InChI key | FOYHOBVZPWIGJM-KCHLEUMXSA-N |
安全信息
| Storage Class Code【储存分类代码】 | 13 - Non Combustible Solids |
| WGK | WGK 3 |
| Personal Protective Equipment【个人防护装备】 | Eyeshields, Gloves, type N95 (US) |
