2-氯-1-甲基吡啶碘化物

C₆H₇ClIN

255.48

3572320

238-288-7

MFCD00011984

24851856

NA.22

2-Chloro-1-methylpyridinium iodide (Mukaiyama reagent), is a commonly used reagent in organic synthesis for the activation of the hydroxy group of alcohols and carboxylic acids. It is used to synthesize derivatives of esters, lactones, amides, lactams, and ketenes from the corresponding carboxylic acids. It is also used as an efficient coupling reagent in the synthesis of peptides because of its low toxicity, simple reaction conditions, and also less expensive than EDC.

2-Chloro-1-methylpyridinium iodide (CMPI) can be used as:

• A dehydrating agent for the conversion of various aldoximes to nitriles, and alcohols into alkyl thiocyanates.
• A cross-linking agent to fabricate biodegradable cross-linked hyaluronic acid film and gelatin membranes for biomedical applications.
• A condensing agent to synthesize various β-lactams from β-amino acids.

200

97%

200 ℃ (dec.) (lit.)

[I-].C[n+]1ccccc1Cl

1S/C6H7ClN.HI/c1-8-5-3-2-4-6(8)7;/h2-5H,1H3;1H/q+1;/p-1

ABFPKTQEQNICFT-UHFFFAOYSA-M

10, 25, 100 g in glass bottle

13 - Non Combustible Solids

WGK 3

dust mask type N95 (US), Eyeshields, Gloves