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(+)-CP-99994 dihydrochloride
产品别名
145148-39-6
(+)-CP-99994 dihydrochloride
(2S,3S)-3-(2-Methoxybenzylamino)-2-phenylpiperidine dihydrochloride
CP-99,994
CP99,994
CP99994
CP-99994
基本信息
| Empirical Formula【经验(实验)分子式】 | C19H24N2O · 2HCl |
| Molecular weight | 369.33 |
| NACRES | NA.77 |
| Biochem/physiol Actions【生化/生理作用】 | (+)-CP-99994 dihydrochloride is an effective and selective non-peptide substance P receptor antagonist. It is synthesized from allylic and homoallylic C-H diamination of 4-phenyl-1-butene. (+)-CP-99994 exhibits anti-emetic activity in ferrets. (+)-CP-99994 is a selective neurokinin (NK)-1 tachykinin antagonist. (+)-CP-99994 binds selectively and with high affinity with a Ki of 0.25 nM in a human cell line. |
产品性质
| Assay【测定】 | ≥98% (HPLC) |
| form【形式】 | powder |
| color【颜色】 | white to beige |
| solubility【溶解性】 | H2O: 15 mg/mL, clear |
| storage temp.【储存温度】 | 2-8℃ |
| packaging【包装】 | 5, 25 mg in glass bottle |
安全信息
| Pictograms【象形图】 | GHS09 |
| Signal word【警示用语：】 | Warning |
| Hazard Statements | H410 |
| Precautionary Statements | P273 - P501 |
| Hazard Classifications【危险分类】 | Aquatic Acute 1 - Aquatic Chronic 1 |
| Storage Class Code【储存分类代码】 | 13 - Non Combustible Solids |
| WGK | WGK 3 |
