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3-(2-Acetoxy-4,6-dimethylphenyl)-3-methylbutyric acid N-succinimidyl ester
产品别名
3-(2-Acetoxy-4,6-dimethylphenyl)-3-methylbutyric acid N-succinimidyl ester
Trimethyl lock NHS
Trimethyl lock succinimidyl ester
3-(2-Acetoxy-4,6-dimethylphenyl)-3-methylbutyric acid N-hydroxysuccinimide ester
结构式
基本信息
| Empirical Formula【经验(实验)分子式】 | C19H23NO6 |
| Molecular weight | 361.39 |
| MDL number | MFCD24386387 |
| PubChem Substance ID【PubChem化学物质编号】 | 329767818 |
| NACRES | NA.22 |
| Application【应用】 | This ′trimethyl lock′ derivative is activated with a succinimidyl ester for modification of amine containing compounds and biomolecules. After modification of your amine of interest, your now ′masked′ molecule can be released by cleavage of the ester, which can be achieved by cellular esterases. This triggers a rapid lactonization reaction of the ′trimethyl lock′ to regenerate your original amine-containing molecule. This approach has been applied to release of fluorophores, peptides, nucleic acids as well as small molecule drugs. |
产品性质
| Assay【测定】 | 95% |
| mp | 107-112 ℃ |
| storage temp.【储存温度】 | 2-8℃ |
| SMILES string | CC(=O)Oc1cc(C)cc(C)c1C(C)(C)CC(=O)ON2C(=O)CCC2=O |
| InChI | 1S/C19H23NO6/c1-11-8-12(2)18(14(9-11)25-13(3)21)19(4,5)10-17(24)26-20-15(22)6-7-16(20)23/h8-9H,6-7,10H2,1-5H3 |
| InChI key | KMNOKEFBKJGRFL-UHFFFAOYSA-N |
| packaging【包装】 | 50 mg in clear glass bottle 250 mg in amber glass bottle |
安全信息
| Pictograms【象形图】 | GHS07 |
| Signal word【警示用语：】 | Warning |
| Hazard Statements | H302 |
| Hazard Classifications【危险分类】 | Acute Tox. 4 Oral |
| Storage Class Code【储存分类代码】 | 11 - Combustible Solids |
| WGK | WGK 3 |
