4-溴甲基-3-硝基苯甲酸

BrCH₂C₆H₃(NO₂)CO₂H

260.04

1970939

MFCD00216575

24866507

NA.22

4-Bromomethyl-3-nitrobenzoic acid (BNBA) is a benzoic acid derivative. It has been synthesized by the nitration of 4-bromomethylbenzoic acid using fuming nitric acid. It participates in the synthesis of 3,4-dihydro-2(1H)-quinazolinones and 3,4-dihydro-1H-quinazolin-2-thiones.

4-Bromomethyl-3-nitrobenzoic acid may be used in the following studies:

• As a reactant in the synthesis of 4-bromomethyl-3-nitrobenzoic acid succinimide ester (BNBA-SE).
• As a reactant in the synthesis of 4-(2-hydroxyethylmercaptylmethyl)-3-nitrobenzoic acid.
• As a reactant in the synthesis of decyl 4-(bromomethyl)-3-nitrobenzoate.
• As a reactant in the synthesis of 4-((2-(hydroxymethyl)phenylamino)methyl)-3-nitrobenzoic acid.
• As a thiol photo-deprotection reagent.
• As a UV-cleavable reagent to functionalize polyacrylamide acryl hydrate (PAAH).
• As a photocleavable linker to form localized photoinversion of surface charges inside the colloidal crystal.
• As a starting material in the synthesis of 2H-indazole based library using parallel solution-phase methods.
• As a reactant in the synthesis of (N-allyloxycarbonyl)-5-aminopent-1-yl 4-bromomethyl-3-nitrobenzoate.

100

97%

127-130 ℃ (lit.)

DMF: soluble(lit.)
dichloromethane: soluble(lit.)

OC(=O)c1ccc(CBr)c(c1)[N+]([O-])=O

1S/C8H6BrNO4/c9-4-6-2-1-5(8(11)12)3-7(6)10(13)14/h1-3H,4H2,(H,11,12)

QMAHVAFURJBOFV-UHFFFAOYSA-N

5 g in glass bottle

GHS05

Danger

H314

P260 - P280 - P303 + P361 + P353 - P304 + P340 + P310 - P305 + P351 + P338 - P363

Skin Corr. 1B

8A - Combustible, corrosive hazardous materials

WGK 3

Eyeshields, Faceshields, Gloves, type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges