4-氰基苯乙酸

C₉H₇NO₂

161.16

226-753-7

MFCD06798066

24882554

4-Cyanophenylacetic acid can be used as a nitrile precursor to synthesize 1,2,4,5-tetrazines by reacting with aliphatic nitriles and hydrazine in the presence of Lewis acid metal catalysts.
It can also be used as a reactant to prepare:

• 4-pyrrolo[1,2-a]quinoxalin-4-ylbenzonitrile by copper-catalyzed reaction with 1-(2-aminoaryl)pyrrole in the presence of 2,2′-bipyridyl as the ligand.
• 4-(1,2-Diphenyl-1H-imidazol-4-yl)benzonitrile by one-pot three-component reaction with N-phenylbenzamidine and nitromethane via activation of C-H and N-H bonds.
• 4-Cyano-N,N-di-2-propen-1-ylbenzeneacetamide by reacting with diallylamine.

100

97%

150-154 ℃ (lit.)

OC(=O)Cc1ccc(cc1)C#N

1S/C9H7NO2/c10-6-8-3-1-7(2-4-8)5-9(11)12/h1-4H,5H2,(H,11,12)

WEBXRQONNWEETE-UHFFFAOYSA-N

1, 5 g in glass bottle

GHS07

Warning

H302 - H315 - H319

P264 - P270 - P280 - P301 + P312 - P302 + P352 - P305 + P351 + P338

Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2

11 - Combustible Solids

WGK 3

dust mask type N95 (US), Eyeshields, Gloves