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5HPP-33
| 产品编号： | 3327526 |
| 规格： | ≥98% (HPLC), solid |
| CAS NO： | 105624-86-0 |
| 包装规格： | 5 MG，25 MG |
| 产品类别： | 进口试剂 |
| 品牌： | Sigma-Aldrich |
| 优惠价： | 立即咨询 |
产品别名
105624-86-0
5HPP-33
2-[2,6-bis(1-Methylethyl)phenyl]-5-hydroxy-1H-isoindole-1,3(2H)-dione
5-Hydroxy-2-(2,6-diisopropylphenyl)-1H-isoindole-1,3-dione
结构式
基本信息
| Empirical Formula【经验(实验)分子式】 | C20H21NO3 |
| Molecular weight | 323.39 |
| MDL number | MFCD03085294 |
| PubChem Substance ID【PubChem化学物质编号】 | 329815265 |
| NACRES | NA.77 |
| Biochem/physiol Actions【生化/生理作用】 | 5HPP-33 is a thalidomide derivative which was reported to be active as anticancer agent through stabilization of the microtubules. 5HPP-33 has shown inhibition of cell proliferation of both estrogen-dependent (MCF-7) and estrogen-independent (MDA-MB-231) breast cancer cells as well as other cell lines. A study in tubulin forming assay reported that 5HPP-33 acts as a microtubule formation inhibitor (IC50=810 nM). |
产品性质
| Quality Level【质量水平】 | 100 |
| Assay【测定】 | ≥98% (HPLC) |
| form【形式】 | solid |
| color【颜色】 | white to off-white |
| solubility【溶解性】 | DMSO: >20 mg/mL |
| storage temp.【储存温度】 | 2-8℃ |
| SMILES string | CC(C)c1cccc(C(C)C)c1N2C(=O)c3ccc(O)cc3C2=O |
| InChI | 1S/C20H21NO3/c1-11(2)14-6-5-7-15(12(3)4)18(14)21-19(23)16-9-8-13(22)10-17(16)20(21)24/h5-12,22H,1-4H3 |
| InChI key | LAKWINYVWJPHQW-UHFFFAOYSA-N |
| packaging【包装】 | 5, 25 mg in glass bottle |
安全信息
| Pictograms【象形图】 | GHS09 |
| Signal word【警示用语：】 | Warning |
| Hazard Statements | H410 |
| Precautionary Statements | P273 - P501 |
| Hazard Classifications【危险分类】 | Aquatic Acute 1 - Aquatic Chronic 1 |
| Storage Class Code【储存分类代码】 | 13 - Non Combustible Solids |
| WGK | WGK 3 |
| Personal Protective Equipment【个人防护装备】 | dust mask type N95 (US), Eyeshields, Gloves |
