6-(二甲氨基)嘌呤

C₇H₉N₅

163.18

7634

213-344-3

MFCD00005573

24893701

6-(Dimethylamino)purine (6-DMAP) is a purine-based metabolite with two condensed heterocyclic rings and two methyl groups linked to the amino group of the purine unit of adenine.

6-(Dimethylamino)purine has been used:

• as a supplement in GR-1 aa medium (bovine medium) for parthenogenetic activation of bovine oocytes to study its potential for embryo development
• in the activation step during the production of nuclear transfer embryos
• as a supplement in HCR2aa medium to activate interspecies embryos derived from interspecies somatic cell nuclear transfer (iSCNT) technique

6-(Dimethylamino)purine (6-DMAP) is a protein kinase and cyclin-dependent kinase inhibitor. It acts as a secondary metabolite and mediates RNA modification. 6-DMAP is a potent cytokinetic inhibitor and is used in parthenogenesis and meiosis studies. It is also used to promote pronuclei formation in mammalian oocytes. 6-DMAP is a dual fluorescence molecule according to femtosecond fluorescence up-conversion spectroscopy studies.

斯克里普斯代谢组学和质谱技术中心独立生成的串联质谱数据可在PDF D2629.pdf 中查看或下载。斯克里普斯代谢物组学和质谱技术中心的METLIN代谢物数据库中有测试代谢物。要了解更多信息，请访问sigma.com/metlin。

synthetic (organic)

100

≥98%

powder

259-262 ℃ (lit.)

water: 50 mg/mL, clear to hazy, colorless to light yellow

−20℃

CN(C)c1ncnc2[nH]cnc12

1S/C7H9N5/c1-12(2)7-5-6(9-3-8-5)10-4-11-7/h3-4H,1-2H3,(H,8,9,10,11)

BVIAOQMSVZHOJM-UHFFFAOYSA-N

100, 250, 500 mg in poly bottle
1 g in poly bottle

13 - Non Combustible Solids

WGK 3

Eyeshields, Gloves, type N95 (US)