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(S)-(-)-Bay K8644
产品别名
98625-26-4
(S)-(-)-Bay K8644
S-(-)-1,4-Dihydro-2,6-dimethyl-5-nitro-4-[2-(trifluoromethyl)phenyl]-3-pyridinecarboxylic acid methyl ester
结构式
基本信息
| Empirical Formula【经验(实验)分子式】 | C16H15F3N2O4 |
| Molecular weight | 356.30 |
| MDL number | MFCD00153769 |
| PubChem Substance ID【PubChem化学物质编号】 | 24891582 |
| NACRES | NA.77 |
| General description【一般描述】 | (S)-(-)-Bay K8644, a dihydropyridine compound is a Ca2+ channel activator. It is an enantiomer of Bay K 8644. |
| Application【应用】 | (S)-(-)-Bay K8644 has been used as a |
| Biochem/physiol Actions【生化/生理作用】 | (S)-(-)-Bay K8644 enhances Ca2+ current, whereas the (+)-Bay K 8644 is a weak Ca2+ channel antagonist. Bay K 8644 is lipophilic and it effectively scavenges superoxide anions. |
| Features and Benefits【特点和优势】 | This compound is featured on the Calcium Channels page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here. |
| Legal Information【法律信息】 | Manufactured and sold with the permission of Bayer AG. |
产品性质
| Quality Level【质量水平】 | 100 |
| Assay【测定】 | ≥98% (HPLC) |
| form【形式】 | solid |
| color【颜色】 | yellow |
| solubility【溶解性】 | H2O: slightly soluble ethanol: soluble (Organic solutions are stable for at least 20 days at RT.) |
| storage temp.【储存温度】 | 2-8℃ |
| SMILES string | COC(=O)C1=C(C)NC(C)=C([C@H]1c2ccccc2C(F)(F)F)[N+]([O-])=O |
| InChI | 1S/C16H15F3N2O4/c1-8-12(15(22)25-3)13(14(21(23)24)9(2)20-8)10-6-4-5-7-11(10)16(17,18)19/h4-7,13,20H,1-3H3/t13-/m0/s1 |
| InChI key | ZFLWDHHVRRZMEI-ZDUSSCGKSA-N |
| Gene Information | human ... ADORA3(140) rat ... Adora1(29290), Adora2a(25369) |
| packaging【包装】 | 1, 5 mg in glass bottle |
安全信息
| Pictograms【象形图】 | GHS07 |
| Signal word【警示用语:】 | Warning |
| Hazard Statements | H315 - H319 |
| Precautionary Statements | P264 - P280 - P302 + P352 - P305 + P351 + P338 - P332 + P313 - P337 + P313 |
| Hazard Classifications【危险分类】 | Eye Irrit. 2 - Skin Irrit. 2 |
| Storage Class Code【储存分类代码】 | 11 - Combustible Solids |
| WGK | WGK 3 |
| Personal Protective Equipment【个人防护装备】 | dust mask type N95 (US), Eyeshields, Gloves |




