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(S)-AMPA
产品价格查看更多规格...
| 产品编号 | 包装单位 | 单价(元) | 国内现货 | 国外库存 | 询价单 |
| 3335607 | 1 MG | 3270 | |||
| 3335607 | 5 MG | 10300 |
产品别名
83643-88-3
(S)-AMPA
(S)-α-Amino-3-hydroxy-5-methylisoxazole-4-propionic acid
结构式
基本信息
| Empirical Formula【经验(实验)分子式】 | C7H10N2O4 |
| Molecular weight | 186.17 |
| MDL number | MFCD00672630 |
| PubChem Substance ID【PubChem化学物质编号】 | 24890421 |
| NACRES | NA.77 |
| General description【一般描述】 | AMPA (α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid) activates excitatory postsynaptic currents (EPSC). |
| Application【应用】 | (S)-AMPA has also been used to activate rostromedial tegmental nucleus (RMTg), to study aversive conditioning in relation with cocaine-induced avoidance behaviors in mice. (S)-AMPA has been used to selectively eliminate the neural cochlear component of adult barn owls by destroying afferent synapses. |
| Biochem/physiol Actions【生化/生理作用】 | Active enantiomer of (RS)-AMPA zwitterion. Potent agonist at the AMPA subclass of ionotropic glutamate receptors. |
| Features and Benefits【特点和优势】 | This compound is a featured product for Neuroscience research. Click here to discover more featured Neuroscience products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm. This compound is featured on the Glutamate Receptors (Ion Channel Family) page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here. |
产品性质
| Quality Level【质量水平】 | 100 |
| Assay【测定】 | ≥98% |
| SMILES string | Cc1onc(O)c1C[C@H](N)C(O)=O |
| InChI | 1S/C7H10N2O4/c1-3-4(6(10)9-13-3)2-5(8)7(11)12/h5H,2,8H2,1H3,(H,9,10)(H,11,12)/t5-/m0/s1 |
| InChI key | UUDAMDVQRQNNHZ-YFKPBYRVSA-N |
| Gene Information | human ... GRIA1(2890), GRIA2(2891), GRIA4(2893), GRIK1(2897) mouse ... Gria1(14799) rat ... Gria1(50592), Gria2(29627), Gria3(29628), Gria4(29629), Grik1(29559), Grik2(54257), Grik4(24406), Grin2a(24409), Grin2b(24410), Grm6(24419) |
安全信息
| Storage Class Code【储存分类代码】 | 13 - Non Combustible Solids |
| WGK | WGK 3 |
| Personal Protective Equipment【个人防护装备】 | Eyeshields, Gloves, type N95 (US) |
