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α-Nicotinamide adenine dinucleotide
产品别名
7298-93-3
α-Nicotinamide adenine dinucleotide
α-Diphosphopyridine nucleotide
α-NAD
α-DPN
结构式
基本信息
| Empirical Formula【经验(实验)分子式】 | C21H27N7O14P2 |
| Molecular weight | 663.43 |
| EC number【EC 号】 | 230-738-0 |
| MDL number | MFCD00134828 |
| PubChem Substance ID【PubChem化学物质编号】 | 24897790 |
| NACRES | NA.51 |
| General description【一般描述】 | Nicotinamide adenine dinucleotide (NAD) is an important cofactor for oxidation-reduction reactions in mitochondria. |
| Application【应用】 | α-Nicotinamide adenine dinucleotide has been used in superoxide dismutase activity of seminal plasma samples and in glutathione peroxidase assay of liver, kidney, testes and brain samples. α-Nicotinamide adenine dinucleotide (αNAD) may be used together with other NAD analogues to study the specificity and kinetics of NAD-dependent and NAD-transporting enzymes and proteins, such as NAD-glycohydrolase(s) and the mitochondrial NAD+ transporter in Saccharomyces cerevisiae. |
| Biochem/physiol Actions【生化/生理作用】 | α-Nicotinamide adenine dinucleotide (α-NAD) is a substrate for renalase. α-NAD, an analog of β-NAD, when used modulates kinetics of NAD dependent enzymes. |
| Other Notes【其他说明】 | α analog of β-NAD |
| Caution【注意】 | This is not the common NAD required in the usual enzyme systems. |
产品性质
| Quality Level【质量水平】 | 200 |
| biological source【生物来源】 | Saccharomyces cerevisiae |
| Assay【测定】 | ≥95% |
| form【形式】 | powder |
| impurities【杂质】 | ≤1% β-isomer |
| storage temp.【储存温度】 | −20℃ |
| SMILES string | NC(=O)c1ccc[n+](c1)[C@H]2O[C@H](COP([O-])(=O)OP(O)(=O)OC[C@H]3O[C@H]([C@H](O)[C@@H]3O)n4cnc5c(N)ncnc45)[C@@H](O)[C@H]2O |
| InChI | 1S/C21H27N7O14P2/c22-17-12-19(25-7-24-17)28(8-26-12)21-16(32)14(30)11(41-21)6-39-44(36,37)42-43(34,35)38-5-10-13(29)15(31)20(40-10)27-3-1-2-9(4-27)18(23)33/h1-4,7-8,10-11,13-16,20-21,29-32H,5-6H2,(H5-,22,23,24,25,33,34,35,36,37)/t10-,11-,13-,14-,15-,16-,20+,21-/m1/s1 |
| InChI key | BAWFJGJZGIEFAR-OPDHFMQKSA-N |
| packaging【包装】 | 10, 25, 100, 250 mg in poly bottle |
安全信息
| Pictograms【象形图】 | GHS07 |
| Signal word【警示用语：】 | Warning |
| Hazard Statements | H315 - H319 - H335 |
| Precautionary Statements | P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338 |
| Hazard Classifications【危险分类】 | Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3 |
| Target Organs【靶器官】 | Respiratory system |
| Storage Class Code【储存分类代码】 | 11 - Combustible Solids |
| WGK | WGK 3 |
| Personal Protective Equipment【个人防护装备】 | dust mask type N95 (US), Eyeshields, Gloves |
