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Ac-YVAD-pNA
产品别名
149231-66-3
Ac-YVAD-pNA
N-α-acetyl-Tyr-Val-Ala-Asp-p-nitroanilide
Caspase-1 substrate (Chromogenic)
N-acetyl-L-tyrosyl-L-valyl-L-alanyl-N-(4-nitrophenyl)-L-α-asparagine
结构式
基本信息
| Empirical Formula【经验(实验)分子式】 | C29H36N6O10 |
| Molecular weight | 628.63 |
| MDL number | MFCD00274387 |
| PubChem Substance ID【PubChem化学物质编号】 | 329825867 |
| NACRES | NA.77 |
| Biochem/physiol Actions【生化/生理作用】 | Ac-YVAD-pNA is a very selective chromogenic substrate for caspase-1, a key mediator of inflammatory processes formerly known as interleukin (IL)-1-converting enzyme. Ac-YVAD-pNA is used to determine caspase-1 activity. Cleavage of Ac-YVAD-pNA by caspase-1 releases pNA (p-nitroanilide), which can be quantified spectrophotometrically at 405 nm. |
产品性质
| Quality Level【质量水平】 | 100 |
| Assay【测定】 | ≥98% (HPLC) |
| form【形式】 | powder |
| color【颜色】 | white to beige |
| storage temp.【储存温度】 | −20℃ |
| SMILES string | O=C([C@H](CC(O)=O)NC([C@H](C)NC([C@H](C(C)C)NC([C@@H](NC(C)=O)CC1=CC=C(O)C=C1)=O)=O)=O)NC2=CC=C([N+]([O-])=O)C=C2 |
| InChI | 1S/C29H36N6O10/c1-15(2)25(34-28(42)22(31-17(4)36)13-18-5-11-21(37)12-6-18)29(43)30-16(3)26(40)33-23(14-24(38)39)27(41)32-19-7-9-20(10-8-19)35(44)45/h5-12,15-16,22-23,25,37H,13-14H2,1-4H3,(H,30,43)(H,31,36)(H,32,41)(H,33,40)(H,34,42)(H,38,39)/t16-,22-,23-,25-/m0/s1 |
| InChI key | YDPNOCSPPGFBPX-XNHCRPTKSA-N |
| packaging【包装】 | 5, 25 mg in glass bottle |
安全信息
| Storage Class Code【储存分类代码】 | 13 - Non Combustible Solids |
| WGK | WGK 3 |
