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Acetyl-Amyloid β-Protein Fragment 15-20 Amide
产品别名
189064-06-0
Acetyl-Amyloid β-Protein Fragment 15-20 Amide
Ac-QKLVFF-NH2
amyloid blocker
结构式
基本信息
| Empirical Formula【经验(实验)分子式】 | C42H63N9O8 |
| Molecular weight | 822.01 |
| MDL number | MFCD17215285 |
| PubChem Substance ID【PubChem化学物质编号】 | 329770908 |
| NACRES | NA.32 |
| Amino Acid Sequence | Ac-Gln-Lys-Leu-Val-Phe-Phe-NH2 |
| Biochem/physiol Actions【生化/生理作用】 | Amyloid plaques characteristic of the Alzheimer brain contain fibrils composed of amyloid beta aggregates. Short peptides containing the sequence KLVFF have been shown to bind specifically to the homologous region in Aβ and are used to prevent full length amyloid fibril formation. |
产品性质
| Quality Level【质量水平】 | 200 |
| Assay【测定】 | ≥97% (HPLC) |
| form【形式】 | powder |
| color【颜色】 | white |
| UniProt accession no.【UniProt登记号】 | P05067 |
| storage temp.【储存温度】 | −20℃ |
| SMILES string | CC(C)C[C@H](NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCC(N)=O)NC(C)=O)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](Cc2ccccc2)C(N)=O |
| InChI | 1S/C42H63N9O8/c1-25(2)22-33(49-38(55)30(18-12-13-21-43)47-39(56)31(46-27(5)52)19-20-35(44)53)41(58)51-36(26(3)4)42(59)50-34(24-29-16-10-7-11-17-29)40(57)48-32(37(45)54)23-28-14-8-6-9-15-28/h6-11,14-17,25-26,30-34,36H,12-13,18-24,43H2,1-5H3,(H2,44,53)(H2,45,54)(H,46,52)(H,47,56)(H,48,57)(H,49,55)(H,50,59)(H,51,58)/t30-,31-,32-,33-,34-,36-/m0/s1 |
| InChI key | DDXTVYDSGCHGAN-PITCCTKHSA-N |
| Gene Information | human ... APP(351) |
| packaging【包装】 | 1 mg in glass bottle |
安全信息
| Storage Class Code【储存分类代码】 | 11 - Combustible Solids |
| WGK | WGK 3 |
| Personal Protective Equipment【个人防护装备】 | Eyeshields, Gloves, type N95 (US) |
