您的位置：首页 > 产品中心 > 55079-83-9， 阿维A
阿维A
Acitretin
产品价格查看更多规格...
| 产品编号 | 包装单位 | 单价(元) | 国内现货 | 国外库存 | 询价单 |
| 3338071 | 25 MG | 1350 |
产品别名
55079-83-9
阿维A
Acitretin
9-(4-Methoxy-2,3,6-trimethylphenyl)-3,7-dimethylnona-2,4,6,8-tetraenoic acid
结构式
基本信息
| Empirical Formula【经验(实验)分子式】 | C21H26O3 |
| Molecular weight | 326.43 |
| EC number【EC 号】 | 259-474-4 |
| MDL number | MFCD00866632 |
| PubChem Substance ID【PubChem化学物质编号】 | 57650239 |
| NACRES | NA.25 |
| Application【应用】 | Acitretin, a retinoid that binds to nuclear receptors and regulates gene expression, is a potent activator of the α-secretase ADAM10 gene expression and apoptosis inducer via the CD95 signalling pathway. Acitretin is a systemic retinoid drug used in the treatment of severe psoriasis. |
| Biochem/physiol Actions【生化/生理作用】 | Synthetic retinoid that is a metabolite of etretinate. Preferentially binds to cellular retinoic acid binding proteins (CRABPs). |
| Other Notes【其他说明】 | Tandem Mass Spectrometry data independently generated by Scripps Center for Metabolomics is available to view or download in PDF. 44707.pdf Tested metabolites are featured on Scripps Center for Metabolomics METLIN Metabolite Database. To learn more, visit sigma.com/metlin. |
产品性质
| Quality Level【质量水平】 | 100 |
| Assay【测定】 | ≥98.0% (HPLC) |
| form【形式】 | powder |
| SMILES string | COc1cc(C)c(\C=C\C(C)=C\C=C\C(C)=C\C(O)=O)c(C)c1C |
| InChI | 1S/C21H26O3/c1-14(8-7-9-15(2)12-21(22)23)10-11-19-16(3)13-20(24-6)18(5)17(19)4/h7-13H,1-6H3,(H,22,23)/b9-7+,11-10+,14-8+,15-12+ |
| InChI key | IHUNBGSDBOWDMA-AQFIFDHZSA-N |
| Gene Information | human ... RARA(5914), RARB(5915), RARG(5916), RXRA(6256), RXRB(6257), RXRG(6258) |
安全信息
| Pictograms【象形图】 | GHS07,GHS08,GHS09 |
| Signal word【警示用语：】 | Danger |
| Hazard Statements | H315 - H319 - H360 - H410 |
| Precautionary Statements | P201 - P273 - P302 + P352 - P305 + P351 + P338 - P308 + P313 |
| Hazard Classifications【危险分类】 | Aquatic Acute 1 - Aquatic Chronic 1 - Eye Irrit. 2 - Repr. 1B - Skin Irrit. 2 |
| Storage Class Code【储存分类代码】 | 6.1D - Non-combustible, acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects |
| WGK | WGK 3 |
| Personal Protective Equipment【个人防护装备】 | Eyeshields, Gloves, type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges |
