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Afzelin

产品编号:3338776
规格:≥90% (LC/MS-UV)
CAS NO:482-39-3
包装规格:1 MG
产品类别:进口试剂
品牌:Sigma-Aldrich
优惠价:立即咨询
产品编号包装单位单价(元)国内现货国外库存询价单
33387761 MG2920
产品别名

482-39-3

Afzelin

Kaempferin

Kaempferol 3-rhamnoside

3,4′,5,7-Tetrahydroxyflavone 3-rhamnoside

Afzeloside

Kaempferol 3-O-alpha-L-rhamnoside

结构式
基本信息
Empirical Formula【经验(实验)分子式】
C21H20O10
Molecular weight
432.38
MDL number
MFCD00210589
PubChem Substance ID【PubChem化学物质编号】
329825042
NACRES
NA.25
General description【一般描述】
Afzelin is a natural product derived from a plant source. Ficus palmata and Nymphaea odoratam are the major sources of afzelin, a flavonol glycoside.
Application【应用】
DNA-protective, antioxidant, anti-inflammatory, UV-absorbing and anti-bacterial activities. Afzelin has been used in HPLC (high performance liquid chromomatography) analysis of Comarum palustre L. extract to detect its major compounds.
DNA-protective, antioxidant, and anti-inflammatory, UV-absorbing activity, anti-bacterial activities.
Biochem/physiol Actions【生化/生理作用】
NOS inhibitor, NADPH oxidase inhibitor, Afzelin is known to possess antibacterial, anti-inflammatory, anti-apoptotic and anti-tumor activities. Afzelin might serve as an effective treatment against P. aeruginosa related diseases. Afzelin also promotes apoptosis to inhibit cell proliferation in breast cancer. It exhibits anti-asthmatic effects in a mouse model.
iNOS inhibitor, NADPH oxidase inhibitor
产品性质
Assay【测定】
≥90% (LC/MS-UV)
form【形式】
solid
solubility【溶解性】
DMSO: 1 mg/mL
storage temp.【储存温度】
−20℃
SMILES string
OC1=CC(O)=C(C(C(O[C@H]2[C@H](O)[C@H](O)[C@@H](O)[C@H](C)O2)=C(C3=CC=C(O)C=C3)O4)=O)C4=C1
InChI
1S/C21H20O10/c1-8-15(25)17(27)18(28)21(29-8)31-20-16(26)14-12(24)6-11(23)7-13(14)30-19(20)9-2-4-10(22)5-3-9/h2-8,15,17-18,21-25,27-28H,1H3/t8-,15-,17+,18+,21-/m0/s1
InChI key
SOSLMHZOJATCCP-AEIZVZFYSA-N
安全信息
Storage Class Code【储存分类代码】
11 - Combustible Solids
WGK
WGK 3
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