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Alosetron hydrochloride
产品价格查看更多规格...
| 产品编号 | 包装单位 | 单价(元) | 国内现货 | 国外库存 | 询价单 |
| 3339605 | 10 MG | 840 | |||
| 3339605 | 50 MG | 3710 |
产品别名
122852-69-1
Alosetron hydrochloride
2,3,4,5-Tetrahydro-5-methyl-2-[(5-methyl-1H-imidazol-4-yl)methyl]-1H-pyrido[4,3-b]indol-1-one hydrochloride
结构式
基本信息
| Empirical Formula【经验(实验)分子式】 | C17H18N4O·HCl |
| Molecular weight | 330.81 |
| MDL number | MFCD09028027 |
| PubChem Substance ID【PubChem化学物质编号】 | 329825350 |
| NACRES | NA.77 |
| Biochem/physiol Actions【生化/生理作用】 | Alosetron is a potent and highly selective antagonist of serotonin 5-HT3 receptors, nonselective cation channels found predominantly in the enteric nervous system of the gastrointestinal tract. These receptors are involved in the regulation of visceral pain, colonic transit and GI secretions that can contribute to the pathophysiology of irritable bowel syndrome (IBS). Alosetron is used clinically for treatment of women with severe diarrhea-predominant IBS. |
产品性质
| Quality Level【质量水平】 | 100 |
| Assay【测定】 | ≥98% (HPLC) |
| form【形式】 | powder |
| storage condition【储存条件】 | desiccated |
| color【颜色】 | white to beige |
| solubility【溶解性】 | H2O: ≥5 mg/mL at warmed |
| storage temp.【储存温度】 | 2-8℃ |
| SMILES string | CN1C2=C(C=CC=C2)C3=C1CCN(CC4=C(C)N=CN4)C3=O.Cl |
| InChI | 1S/C17H18N4O.ClH/c1-11-13(19-10-18-11)9-21-8-7-15-16(17(21)22)12-5-3-4-6-14(12)20(15)2;/h3-6,10H,7-9H2,1-2H3,(H,18,19);1H |
| InChI key | FNYQZOVOVDSGJH-UHFFFAOYSA-N |
| Gene Information | human ... HTR3A(3359) |
| packaging【包装】 | 10, 50 mg in glass bottle |
安全信息
| Pictograms【象形图】 | GHS06 |
| Signal word【警示用语：】 | Danger |
| Hazard Statements | H301 - H319 - H412 |
| Precautionary Statements | P273 - P301 + P310 + P330 - P305 + P351 + P338 |
| Hazard Classifications【危险分类】 | Acute Tox. 3 Oral - Aquatic Chronic 3 - Eye Irrit. 2 |
| Storage Class Code【储存分类代码】 | 6.1C - Combustible, acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects |
| WGK | WGK 3 |
