您的位置：首页 > 产品中心 > Anti-APAF1 antibody produced in chicken
Anti-APAF1 antibody produced in chicken
| 产品编号： | 3345209 |
| 规格： | affinity isolated antibody, buffered aqueous solution |
| 包装规格： | 50 μG |
| 产品类别： | 进口试剂 |
| 品牌： | Sigma-Aldrich |
| 优惠价： | 立即咨询 |
产品别名
Anti-APAF1 antibody produced in chicken
Anti-Apoptotic protease-activating factor 1
基本信息
| MDL number | MFCD02095846 |
| NACRES | NA.41 |
| Immunogen【免疫原】 | Immunogen Sequence: GI # 32483361, sequence 307-388 Recombinant apoptotic protease activating factor isoform d |
| Application【应用】 | Anti-APAF1 antibody produced in chicken is suitable for western blotting analysis at a dilution of 1:500, for tissue or cell staining at a dilution of 1:200. |
| Biochem/physiol Actions【生化/生理作用】 | Apoptotic protease activating factor 1 is a human homolog of C. elegans CED-4 gene and is a key regulator gene of apoptosis. It acts as a central component of the intrinsic pathway of apoptosis. Loss of APAF-1 expression is involved with chemorefractory malignant melanoma and neuronal cell differentiation. Over expression of this gene is related to an undifferentiated state in the testicular germ cell tumor (TGCT) pathway and is involved in carcinogenesis of germ cell tumors. APAF-1, when bound to cytochrome c, may trigger the activation of caspase-3 leading to apoptosis. |
| Physical form【外形】 | Solution in phosphate buffered saline containing 0.02% sodium azide. |
产品性质
| biological source【生物来源】 | chicken |
| conjugate【偶联物】 | unconjugated |
| antibody form【抗体形式】 | affinity isolated antibody |
| antibody product type | primary antibodies |
| clone【克隆】 | polyclonal |
| form【形式】 | buffered aqueous solution |
| species reactivity | human, mouse |
| manufacturer/tradename | Genway 15-288-21169 |
| technique(s) | western blot: suitable |
| NCBI accession no.【NCBI登记号】 | NP_863658.1 |
| UniProt accession no.【UniProt登记号】 | O14727 |
| shipped in【运输】 | wet ice |
| storage temp.【储存温度】 | −20℃ |
| Gene Information | human ... APAF1(317) |
安全信息
| Storage Class Code【储存分类代码】 | 12 - Non Combustible Liquids |
| WGK | WGK 1 |
| Personal Protective Equipment【个人防护装备】 | Eyeshields, Gloves, multi-purpose combination respirator cartridge (US) |
