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Anti-Aurora Kinase A/B/C antibody, Rabbit monoclonal
| 产品编号： | 3347020 |
| 规格： | recombinant, expressed in proprietary host, clone SP201, affinity isolated antibody |
| 包装规格： | 100 μL |
| 产品类别： | 进口试剂 |
| 品牌： | Sigma-Aldrich |
| 优惠价： | 立即咨询 |
基本信息
| NACRES | NA.41 |
| General description【一般描述】 | Aurora kinases are highly conserved serine/threonine kinases in eukaryotes, involved in many processes during cell division. Three aurora kinases have been identified in humans and designated as Aurora-A, -B, and -C. They mostly consist of two domains: a regulatory domain in the NH2 terminus and a catalytic domain in the COOH terminus. Aurora A regulates centrosome function during M phase and is required for initial activation of CDK1 at centrosomes and phosphorylates numerous target proteins. Over-expression of Aurora-A or -B protein can lead to aneuploid cells and is frequently observed in various human cancers such as prostate, breast, and esophageal cancers. |
| Immunogen【免疫原】 | Synthetic peptide near the C-terminus of human Aurora kinase A, B, and C proteins. |
| Features and Benefits【特点和优势】 | Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more. |
| Physical form【外形】 | 0.1 ml rabbit monoclonal antibody purified by protein A/G in PBS/1% BSA buffer pH 7.6 with less than 0.1% sodium azide. |
产品性质
| biological source【生物来源】 | rabbit |
| Quality Level【质量水平】 | 100 |
| recombinant【重组】 | expressed in proprietary host |
| conjugate【偶联物】 | unconjugated |
| antibody form【抗体形式】 | affinity isolated antibody |
| antibody product type | primary antibodies |
| clone【克隆】 | SP201, monoclonal |
| species reactivity | human (tested) |
| species reactivity (predicted by homology) | frog, bovine, rat, pig |
| technique(s) | flow cytometry: 1:400 immunohistochemistry: 1:100 |
| isotype【同位素/亚型】 | IgG |
| UniProt accession no.【UniProt登记号】 | O14965 |
| shipped in【运输】 | wet ice |
| storage temp.【储存温度】 | 2-8℃ |
| Gene Information | human ... AURKA(6790) |
产品说明
| Disclaimer【免责声明】 | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
安全信息
| Storage Class Code【储存分类代码】 | 12 - Non Combustible Liquids |
| WGK | WGK 2 |
