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Anti-CD163 antibody produced in rabbit
产品别名
Anti-CD163 antibody produced in rabbit
M130
MM130
产品性质
biological source【生物来源】 | rabbit |
Quality Level【质量水平】 | 100 |
antibody form【抗体形式】 | affinity isolated antibody |
antibody product type | primary antibodies |
clone【克隆】 | polyclonal |
form【形式】 | buffered aqueous solution |
species reactivity | human |
concentration【浓度】 | 2.9 mg/mL |
technique(s) | immunohistochemistry: 1:25- 1:100 |
isotype【同位素/亚型】 | IgG |
accession no.【登记号】 | NP_004235.4 |
UniProt accession no.【UniProt登记号】 | Q86VB7 |
shipped in【运输】 | wet ice |
storage temp.【储存温度】 | −20℃ |
Gene Information | human ... CD163(9332) |
基本信息
General description【一般描述】 | Cluster of differentiation 163 (CD163) is a hemoglobin scavenger receptor, encoded by a gene mapped to human chromosome 12p13.31. It is expressed on the surface of activated macrophages. The encoded protein is a member of scavenger receptor cysteine-rich family (SRCR) and is specifically expressed on cells of the monocyte/macrophage lineage. |
Specificity【特异性】 | The antibody detects endogenous levels of total CD163 protein. |
Immunogen【免疫原】 | Synthetic peptide corresponding to residues near the C terminal of human CD163 molecule |
Biochem/physiol Actions【生化/生理作用】 | Cluster of differentiation 163 (CD163) modulates anti-inflammatory functions and has a role in hemoglobin-haptoglobin clearance. Various cytokines influence the expression of CD163. It may be associated with hepatocellular carcinoma. Soluble CD163 level in serum acts as a potent indicator of the progression of cirrhosis and portal hypertension. |
Features and Benefits【特点和优势】 | Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more. |
Physical form【外形】 | Rabbit IgG in pH7.3 PBS, 0.05% NaN3, 50% Glycerol. |
产品说明
Disclaimer【免责声明】 | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
安全信息
Storage Class Code【储存分类代码】 | 10 - Combustible liquids |
WGK | WGK 1 |