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Anti-CDX4 (AB2) antibody produced in rabbit
产品别名
Anti-CDX4 (AB2) antibody produced in rabbit
Anti-caudal type homeobox transcription factor 4
基本信息
| NACRES | NA.41 |
| General description【一般描述】 | Caudal related homeobox (Cdx) genes are known to modulate axial elongation and patterning in many vertebrate embryos. Cdx4 regulates the ontogenesis of placental labyrinth in mice. Furthermore, Cdx4 is known to dysregulate Hox gene expression which causes acute myeloid leukemia in mouse models. Rabbit Anti-CDX4 (AB2) antibody recognizes rat, mouse, bovine, human, canine, zebrafish, and chicken CDX4. |
| Immunogen【免疫原】 | Synthetic peptide directed towards the middle region of human CDX4 |
| Application【应用】 | Rabbit Anti-CDX4 (AB2) antibody is suitable for use in western blot assays at a concentration of 1.0μg/ml. The product can also be used for immunohistochemistry applications at 4-8μg/ml (using paraffin-embedded tissues). |
| Biochem/physiol Actions【生化/生理作用】 | CDX are homeodomain transcription factors related to the Drosophila caudal gene. The vertebrate CDX have been implicated in the development of the posterior embryo. Several signaling molecules, notably retinoic acid (RA) and members of the Wnt (wingless) and fibroblast growth factor (FGF) families, are also implicated in patterning of the posterior vertebrate embryo. CDX family is the target of Wnt, RA and FGF signaling, suggesting that CDX factors act to convey the activity of these signaling molecules to Hox genes. |
| Sequence【序列】 | Synthetic peptide located within the following region: TDHQRLELEKEFHCNRYITIQRKSELAVNLGLSERQVKIWFQNRRAKERK |
| Physical form【外形】 | Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
产品性质
| biological source【生物来源】 | rabbit |
| Quality Level【质量水平】 | 100 |
| conjugate【偶联物】 | unconjugated |
| antibody form【抗体形式】 | affinity isolated antibody |
| antibody product type | primary antibodies |
| clone【克隆】 | polyclonal |
| form【形式】 | buffered aqueous solution |
| mol wt【分子量】 | 30 kDa |
| species reactivity | human, dog |
| concentration【浓度】 | 0.5 mg - 1 mg/mL |
| technique(s) | immunohistochemistry: suitable western blot: suitable |
| NCBI accession no.【NCBI登记号】 | NP_005184 |
| UniProt accession no.【UniProt登记号】 | O14627 |
| shipped in【运输】 | wet ice |
| storage temp.【储存温度】 | −20℃ |
| Gene Information | human ... CDX4(1046) |
产品说明
| Disclaimer【免责声明】 | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
安全信息
| Storage Class Code【储存分类代码】 | 12 - Non Combustible Liquids |
| WGK | WGK 3 |
