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Anti-CLIC1 (AB1) antibody produced in rabbit
产品别名
Anti-CLIC1 (AB1) antibody produced in rabbit
Anti-chloride intracellular channel 1
基本信息
NACRES | NA.41 |
General description【一般描述】 | CLIC1 codes for an intracellular chloride ion channel protein. Studies have reported that oxidized CLIC1 dimers can form chloride ion channels in synthetic vesicles and bilayers. Furthermore, in the absence of detergents, CLIC1 can spontaneously insert into preformed membranes. Rabbit Anti-CLIC1 antibody recognizes bovine, rabbit, human, mouse, and rat CLIC1. |
Immunogen【免疫原】 | Synthetic peptide directed towards the C terminal region of human CLIC1 |
Application【应用】 | Rabbit Anti-CLIC1 antibody is suitable for western blot applications at a concentration of 0.5 μg/ml |
Biochem/physiol Actions【生化/生理作用】 | Chloride channels are a diverse group of proteins that regulate fundamental cellular processes including stabilization of cell membrane potential, transepithelial transport, maintenance of intracellular pH, and regulation of cell volume. Chloride intracellular channel 1 (CLIon Channel1) is a member of the p64 family; the protein localizes principally to the cell nucleus and exhibits both nuclear and plasma membrane chloride ion channel activity. |
Sequence【序列】 | Synthetic peptide located within the following region: LTLADCNLLPKLHIVQVVCKKYRGFTIPEAFRGVHRYLSNAYAREEFAST |
Physical form【外形】 | Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
产品性质
biological source【生物来源】 | rabbit |
Quality Level【质量水平】 | 100 |
conjugate【偶联物】 | unconjugated |
antibody form【抗体形式】 | affinity isolated antibody |
antibody product type | primary antibodies |
clone【克隆】 | polyclonal |
form【形式】 | buffered aqueous solution |
mol wt【分子量】 | 27 kDa |
species reactivity | rat, human, mouse, horse |
concentration【浓度】 | 0.5 mg - 1 mg/mL |
technique(s) | western blot: suitable |
NCBI accession no.【NCBI登记号】 | NP_001279 |
UniProt accession no.【UniProt登记号】 | Q502X1 |
shipped in【运输】 | wet ice |
storage temp.【储存温度】 | −20℃ |
Gene Information | human ... CLIC1(1192) |
产品说明
Disclaimer【免责声明】 | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
安全信息
Storage Class Code【储存分类代码】 | 12 - Non Combustible Liquids |
WGK | WGK 2 |