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Anti-CLIC2 (AB1) antibody produced in rabbit
产品别名
Anti-CLIC2 (AB1) antibody produced in rabbit
Anti-Chloride intracellular channel 2
基本信息
| NACRES | NA.41 |
| General description【一般描述】 | CLIC2 codes for an intracellular chloride ion channel protein. CLIC2 forms pH-dependent chloride channels in in vitro conditions. Its chloride channel functions are modulated by pH levels and redox status. It interacts with skeletal ryanodine receptor (RyR1). Rabbit Anti-CLIC2 antibody recognizes chicken, mouse, rat, rabbit, human, bovine, and canine CLIC2. |
| Immunogen【免疫原】 | Synthetic peptide directed towards the C terminal region of human CLIC2 |
| Application【应用】 | Rabbit Anti-CLIC2 antibody is suitable for western blot applications at a concentration of 1.25 μg/ml. |
| Biochem/physiol Actions【生化/生理作用】 | Chloride intracellular channel 2 is a member of the p64 family, a diverse group of proteins that regulate fundamental cellular processes including stabilization of cell membrane potential, transepithelial transport, maintenance of intracellular pH, and regulation of cell volume. CLIon Channel 2 encodes a protein that is detected in fetal liver and adult skeletal muscle tissue. CLIon Channel2 maps to the candidate region on chromosome X for incontinentia pigmenti. |
| Sequence【序列】 | Synthetic peptide located within the following region: SAEEPPVSRRLFLDGDQLTLADCSLLPKLNIIKVAAKKYRDFDIPAEFSG |
| Physical form【外形】 | Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
产品性质
| biological source【生物来源】 | rabbit |
| Quality Level【质量水平】 | 100 |
| conjugate【偶联物】 | unconjugated |
| antibody form【抗体形式】 | IgG fraction of antiserum |
| antibody product type | primary antibodies |
| clone【克隆】 | polyclonal |
| form【形式】 | buffered aqueous solution |
| mol wt【分子量】 | 27 kDa |
| species reactivity | horse, human, dog, rat, guinea pig, rabbit |
| concentration【浓度】 | 0.5 mg - 1 mg/mL |
| technique(s) | western blot: suitable |
| NCBI accession no.【NCBI登记号】 | NP_001280 |
| UniProt accession no.【UniProt登记号】 | O15247 |
| shipped in【运输】 | wet ice |
| storage temp.【储存温度】 | −20℃ |
| Gene Information | human ... CLIC2(1193) |
产品说明
| Disclaimer【免责声明】 | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
安全信息
| Storage Class Code【储存分类代码】 | 10 - Combustible liquids |
| WGK | WGK 3 |
