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Anti-Clusterin antibody produced in rabbit
| 产品编号： | 3354128 |
| 规格： | affinity isolated antibody, buffered aqueous solution |
| 包装规格： | 100 μG |
| 产品类别： | 进口试剂 |
| 品牌： | Sigma-Aldrich |
| 优惠价： | 立即咨询 |
产品别名
Anti-Clusterin antibody produced in rabbit
Anti-APOJ
Anti-CLI
Anti-Apolipoprotein J
Anti-Complement lysis inhibitor
基本信息
| MDL number | MFCD01092275 |
| NACRES | NA.41 |
| General description【一般描述】 | The Clusterin (CLU) gene is mapped to human chromosome 8p21.1. The encoded protein is a chaperone and is conserved along with evolution. It is present in human tissues and fluids. |
| Immunogen【免疫原】 | Clusterin antibody was raised recombinant human Clusterin isoform 1. |
| Application【应用】 | Anti-Clusterin antibody produced in rabbit has been used in immunohistochemical (IHC) staining (1:1,000 & 1:100). |
| Biochem/physiol Actions【生化/生理作用】 | Clusterin (CLU) is a multifunctional plasma protein and a fluid-phase complement inhibitor. It mediates the complement terminal pathway. Clusterin is an ATP-independent small heat shock protein-like chaperone. It functions as a redox sensor and a lipid transporter. Clusterin is associated with many age-related diseases such as neurodegeneration and metabolic syndrome. It is involved in cancer progression, promotion, metastasis, and chemoresistance. Increased serum CLU levels are observed in type 2 diabetes (T2D). It is known to suppress proteotoxicity. Clusterin might show anti or proapoptotic activities. This protein is associated with different functions of the brain. A single nucleotide polymorphism (SNP) in the CLU gene might cause the development of late-onset Alzheimer′s disease (LOAD). |
| Features and Benefits【特点和优势】 | Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more. |
| Physical form【外形】 | Supplied in PBS with 0.02% sodium azide. |
产品性质
| biological source【生物来源】 | rabbit |
| conjugate【偶联物】 | unconjugated |
| antibody form【抗体形式】 | affinity isolated antibody |
| antibody product type | primary antibodies |
| clone【克隆】 | polyclonal |
| form【形式】 | buffered aqueous solution |
| species reactivity | mouse, human |
| technique(s) | immunofluorescence: suitable immunohistochemistry: suitable indirect ELISA: suitable western blot: suitable |
| NCBI accession no.【NCBI登记号】 | NP_001822 |
| UniProt accession no.【UniProt登记号】 | P10909 |
| shipped in【运输】 | dry ice |
| storage temp.【储存温度】 | −20℃ |
| Gene Information | human ... CLU(1191) |
产品说明
| Disclaimer【免责声明】 | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
安全信息
| Storage Class Code【储存分类代码】 | 12 - Non Combustible Liquids |
| WGK | WGK 2 |
