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Anti-CNOT2 antibody produced in rabbit
产品别名
Anti-CNOT2 antibody produced in rabbit
Anti-CCR4-NOT transcription complex, subunit 2
基本信息
| NACRES | NA.41 |
| General description【一般描述】 | CNOT2 forms a part of the transcriptional regulator, the Ccr4-Not complex, and can repress promoter functions. Studies have reported that depletion of CNOT2 inhibits CCR4-NOT deadenylase and causes apoptosis in cells. Furthermore, the SMRT/NCoR-HDAC3 complex is known to be a cofactor of CNOT2-mediated transcriptional repression. Rabbit Anti-CNOT2 antibody recognizes bovine, human, mouse, rat, canine, and chicken CNOT2. |
| Immunogen【免疫原】 | Synthetic peptide directed towards the middle region of human CNOT2 |
| Application【应用】 | Rabbit Anti-CNOT2 antibody can be used for western blot applications at a concentration of 1.25μg/ml. |
| Biochem/physiol Actions【生化/生理作用】 | CNOT2 is one of the subunits of the CCR4-NOT complex,which functions as general transcription regulation complex. |
| Sequence【序列】 | Synthetic peptide located within the following region: SYKDPTSSNDDSKSNLNTSGKTTSSTDGPKFPGDKSSTTQNNNQQKKGIQ |
| Physical form【外形】 | Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
产品性质
| biological source【生物来源】 | rabbit |
| Quality Level【质量水平】 | 100 |
| conjugate【偶联物】 | unconjugated |
| antibody form【抗体形式】 | IgG fraction of antiserum |
| antibody product type | primary antibodies |
| clone【克隆】 | polyclonal |
| form【形式】 | buffered aqueous solution |
| mol wt【分子量】 | 40 kDa |
| species reactivity | human, bovine, rabbit, horse, guinea pig, rat, dog, mouse |
| concentration【浓度】 | 0.5 mg - 1 mg/mL |
| technique(s) | western blot: suitable |
| NCBI accession no.【NCBI登记号】 | NP_055330 |
| UniProt accession no.【UniProt登记号】 | Q9NZN8-2 |
| shipped in【运输】 | wet ice |
| storage temp.【储存温度】 | −20℃ |
| Gene Information | human ... CNOT2(4848) |
产品说明
| Disclaimer【免责声明】 | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
安全信息
| Storage Class Code【储存分类代码】 | 12 - Non Combustible Liquids |
| WGK | WGK 3 |
