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Anti-COG2 antibody produced in rabbit
产品别名
Anti-COG2 antibody produced in rabbit
Anti-Low density lipoprotein receptor defect C-complementing protein
Anti-component of oligomeric golgi complex 2
Anti-LDLC
基本信息
| NACRES | NA.41 |
| General description【一般描述】 | Conserved oligomeric Golgi (COG) complex 2 is also known as LDLC. COG complex is a multi-subunit protein complex, composed of eight distinct subunits. This protein is highly conserved with two heterotrimeric groups, Cog2-Cog3- Cog4 and Cog5-Cog6-Cog7 in its structure. |
| Immunogen【免疫原】 | synthetic peptide corresponding to the C-terminal region of human COG2, conjugated to KLH. The corresponding sequence is identical in monkey and bovine and differs by four amino acids in rat and mouse COG2. |
| Application【应用】 | Anti-COG2 antibody produced in rabbit has been used in:
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| Biochem/physiol Actions【生化/生理作用】 | Conserved oligomeric Golgi (COG) complex 2 regulates membrane trafficking and maintenance of Golgi glycosylation machinery in eukaryotic cells. COG2 is needed for normal Golgi morphology and function. COG2 interacts with p115 (golgin), a vesicle tethering protein that functions in endoplasmic reticulum-Golgi trafficking. This interaction is required for Golgi integrity. |
| Physical form【外形】 | Solution in 0.01 M phosphate buffered saline pH 7.4, containing 15 mM sodium azide. |
产品性质
| biological source【生物来源】 | rabbit |
| conjugate【偶联物】 | unconjugated |
| antibody form【抗体形式】 | IgG fraction of antiserum |
| antibody product type | primary antibodies |
| clone【克隆】 | polyclonal |
| form【形式】 | buffered aqueous solution |
| mol wt【分子量】 | antigen ~83 kDa |
| species reactivity | human |
| technique(s) | immunoblotting: 1:1000-1:2000 using whole extracts of hamster CHO cells. immunoprecipitation (IP): 2.5-5.0 μL using lysates of human HeLa cells indirect immunofluorescence: 1:2,500-1:5,000 using human HeLa cells. |
| UniProt accession no.【UniProt登记号】 | Q14746 |
| shipped in【运输】 | dry ice |
| storage temp.【储存温度】 | −20℃ |
| Gene Information | human ... COG2(22796) |
产品说明
| Disclaimer【免责声明】 | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
安全信息
| Storage Class Code【储存分类代码】 | 12 - Non Combustible Liquids |
| WGK | WGK 2 |
