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Anti-CPEB2 antibody produced in rabbit
产品别名
Anti-CPEB2 antibody produced in rabbit
Anti-Cytoplasmic polyadenylation element binding protein 2
基本信息
| NACRES | NA.41 |
| General description【一般描述】 | Cytoplasmic polyadenylation element binding protein 2 (CPEB2) is an RNA binding protein that regulates cytoplasmic polyadenylation and translation of mRNAs in germ cells and neural cells. CPEB2 is involved in the regulation of the oxygen homoeostasis transcriptional master regulator gene hypoxia-inducible factor-1 (HIF-1). |
| Specificity【特异性】 | Anti-CPEB2 polyclonal antibody reacts with bovine, chicken, canine, pig, human, mouse, rat, and zebrafish cytoplasmic polyadenylation element binding protein 2 proteins. |
| Immunogen【免疫原】 | Synthetic peptide directed towards the middle region of human CPEB2 |
| Application【应用】 | Anti-CPEB2 polyclonal antibody is used to tag cytoplasmic polyadenylation element binding protein 2 proteins for detection and quantitation by Western blotting and in cells and tissues by immunohistochemical (IHC) techniques. It is used as a probe to study the role of CPEB2 in the regulation of mRNA transcription in germ cells and neural cells. |
| Biochem/physiol Actions【生化/生理作用】 | CPEB2 is highly similar to cytoplasmic polyadenylation element binding protein (CPEB), an mRNA-binding protein that regulates cytoplasmic polyadenylation of mRNA as a trans factor in oogenesis and spermatogenesis. Studies of the similar gene in mice suggested a possible role of this protein in transcriptionally inactive haploid spermatids. |
| Sequence【序列】 | Synthetic peptide located within the following region: DTDPELKYPKGAGRVAFSNQQSYIAAISARFVQLQHGDIDKRVEVKPYVL |
| Physical form【外形】 | Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
产品性质
| biological source【生物来源】 | rabbit |
| Quality Level【质量水平】 | 100 |
| conjugate【偶联物】 | unconjugated |
| antibody form【抗体形式】 | IgG fraction of antiserum |
| antibody product type | primary antibodies |
| clone【克隆】 | polyclonal |
| form【形式】 | buffered aqueous solution |
| mol wt【分子量】 | 37 kDa |
| species reactivity | horse, mouse, bovine, human, guinea pig, rabbit, dog, rat |
| concentration【浓度】 | 0.5 mg - 1 mg/mL |
| technique(s) | western blot: suitable |
| NCBI accession no.【NCBI登记号】 | NP_872291 |
| UniProt accession no.【UniProt登记号】 | Q7Z5Q1 |
| shipped in【运输】 | wet ice |
| storage temp.【储存温度】 | −20℃ |
| Gene Information | human ... CPEB2(132864) |
产品说明
| Disclaimer【免责声明】 | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
安全信息
| Storage Class Code【储存分类代码】 | 12 - Non Combustible Liquids |
| WGK | WGK 3 |
