Anti-CRHR2 antibody produced in mouse

NA.41

CRHR2 (corticotropin releasing hormone receptor 2) gene is located in human chromosome 7p14.3. The encoded protein is a G-coupled protein receptor that belongs to the family of corticotropin releasing factor (CRF). The gene is widely expressed in the peripheral organs such as the heart, skeletal muscle, intestines and airway epithelium.

CRHR2 (NP_001874.2, 1 a.a. ~ 411 a.a) full-length human protein.

Sequence
MDAALLHSLLEANCSLALAEELLLDGWGPPLDPEGPYSYCNTTLDQIGTCWPRSAAGALVERPCPEYFNGVKYNTTRNAYRECLENGTWASKINYSQCEPILDDKQRKYDLHYRIALVVNYLGHCVSVAALVAAFLLFLALRSIRCLRNVIHWNLITTFILRNVMWFLLQLVDHEVHESNEVWCRCITTIFNYFVVTNFFWMFVEGCYLHTAIVMTYSTERLRKCLFLFIGWCIPFPIIVAWAIGKLYYENEQCWFGKEPGDLVDYIYQGPIILVLLINFVFLFNIVRILMTKLRASTTSETIQYRKAVKATLVLLPLLGITYMLFFVNPGEDDLSQIMFIYFNSFLQSFQGFFVSVFYCFFNGEVRSAVRKRWHRWQDHHSLRVPMARAMSIPTSPTRISFHSIKQTAAV

CRHR2 (corticotropin releasing hormone receptor 2) is known to control immune responses and stress hormone system, especially the local peripheral inflammatory responses. In brain, activation of CRHR2 is believed to reduce anxiety.

Solution in phosphate buffered saline, pH 7.4

100

mouse

unconjugated

purified immunoglobulin

primary antibodies

polyclonal

buffered aqueous solution

human

western blot: 1 μg/mL

NM_001883

Q13324

dry ice

−20℃

human ... CRHR2(1395)

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