您的位置:首页 > 产品中心 > Anti-CRHR2 antibody produced in rabbit
Anti-CRHR2 antibody produced in rabbit
产品别名
Anti-CRHR2 antibody produced in rabbit
CRF-R 2
Corticotropin-releasing hormone receptor 2
CRF2
Corticotropin-releasing factor receptor 2
CRH-R 2
产品性质
biological source【生物来源】 | rabbit |
Quality Level【质量水平】 | 100 |
conjugate【偶联物】 | unconjugated |
antibody form【抗体形式】 | affinity isolated antibody |
antibody product type | primary antibodies |
clone【克隆】 | polyclonal |
form【形式】 | buffered aqueous solution |
mol wt【分子量】 | antigen 47 kDa |
species reactivity | mouse, human, rat |
concentration【浓度】 | ~1 mg/mL |
technique(s) | ELISA: 1:10000 immunofluorescence: 1:100-1:500 western blot: 1:500-1:1000 |
NCBI accession no.【NCBI登记号】 | Q13324 |
UniProt accession no.【UniProt登记号】 | Q13324 |
shipped in【运输】 | wet ice |
storage temp.【储存温度】 | −20℃ |
Gene Information | human ... CRHR2(1395) |
基本信息
General description【一般描述】 | The CRHR2 (corticotropin releasing hormone receptor 2) gene is a member of G protein coupled receptors (GPCRs) family. It is located on human chromosome 7p21-p15. It has 12 exons and approximately 50,000 base pairs (Kbp). It has 3 isoforms, such as CRHR2α β and γ out of which, CRHR2γ is mostly expressed in the brain and CRHR2α 2β are expressed in the brain and smooth muscle. Anti-CRHR2 antibody detects endogenous levels of total CRHR2 protein. |
Immunogen【免疫原】 | The antiserum was produced against synthesized peptide derived from human CRHR2. Immunogen Range: 71-120 |
Application【应用】 | Anti-CRHR2 antibody has been used in immunoprecipitation and western blotting .{6,7} Applications in which this antibody has been used successfully, and the associated peer-reviewed papers, are given below. Western Blotting (1 paper) |
Biochem/physiol Actions【生化/生理作用】 | CRHR2 (corticotropin releasing hormone receptor 2) is involved in the relaxation of smooth muscle response and may affect the response of acute airway bronchodilator to short acting β2 agonist treatment of asthma. Signaling pathways of CRHR2 modulate the hypothalamic-pituitary-adrenocortical axis. |
Features and Benefits【特点和优势】 | Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more. |
Physical form【外形】 | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
产品说明
Disclaimer【免责声明】 | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
安全信息
Storage Class Code【储存分类代码】 | 12 - Non Combustible Liquids |
WGK | nwg |