Anti-CRTH2 (GRP44) antibody produced in rabbit

MFCD08064414

NA.41

peptide corresponding to the human CRTH2 (GRP44) protein, near the C-terminus (amino acids 329-348).

Anti-CRTH2 (GRP44) antibody produced in rabbit is suitable for western blotting at a working dilution of 1:500-1:1,000 using CRTH2- transfected Jurkat cells.

CRTH2 (chemoattractant receptor-homologous molecule), is known as the putative G protein-coupled receptor (GP44), is expressed on T helper 2 (Th2) cells. It is also referred as DP2, DL1R and CD294. It′s a human protein and belongs to G protein-coupled leukocyte chemo attractant receptor family. It is not expressed on human amniocytes or myocytes. On activation of CRTH2, PGD(2) induces human osteoclast apoptosis and the apoptosis intrinsic pathway. CRTH2, CD4 and T cells all together may be involved in the pathogenesis of IgG4-related Lacrimal gland enlargement (LGE) causing Mikulicz′s disease (MD).

Solution of 1 mg/mL in phosphate buffered saline containing 0.02% sodium azide.

rabbit

200

unconjugated

affinity isolated antibody

primary antibodies

polyclonal

buffered aqueous solution

antigen ~43 kDa by calculation

rat, mouse, human

western blot: 1:500-1:1,000 using CRTH2-transfected Jurkat cells

dry ice

−20℃

human ... GPR44(11251)
mouse ... Gpr44(14764)
rat ... Gpr44(309212)

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12 - Non Combustible Liquids

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