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Anti-CSTF3 (N-terminal) antibody produced in rabbit
| 产品编号： | 3355622 |
| 规格： | IgG fraction of antiserum, buffered aqueous solution |
| 包装规格： | 200 μL |
| 产品类别： | 进口试剂 |
| 品牌： | Sigma-Aldrich |
| 优惠价： | 立即咨询 |
产品别名
Anti-CSTF3 (N-terminal) antibody produced in rabbit
Anti-Cleavage stimulation factor 77
Anti-CSTF-77
产品性质
| biological source【生物来源】 | rabbit |
| Quality Level【质量水平】 | 200 |
| conjugate【偶联物】 | unconjugated |
| antibody form【抗体形式】 | IgG fraction of antiserum |
| antibody product type | primary antibodies |
| clone【克隆】 | polyclonal |
| form【形式】 | buffered aqueous solution |
| mol wt【分子量】 | antigen ~77 kDa |
| species reactivity | human |
| technique(s) | immunoprecipitation (IP): 2.5-5 μL using lysates of HEK-293T cells western blot: 1:500-1:1000 using lysates of HEK-293T |
| UniProt accession no.【UniProt登记号】 | Q12996 |
| shipped in【运输】 | dry ice |
| storage temp.【储存温度】 | −20℃ |
| Gene Information | human ... CSTF3(1479) |
基本信息
| General description【一般描述】 | Cleavage stimulatory factor (CstF3), also called CSTF-77, is a component of CstF heterotrimer. It has a proline-rich domain and the gene is mapped to human chromosome 11p13. CstF3 contains 12 half-A-TPR (HAT) repeats followed by a proline-rich segment. |
| Specificity【特异性】 | Anti-CSTF3 (N-terminal) specifically recognizes human CSTF3 (also known as Cleavage stimulation factor 77, CSTF-77, CF-1 77 kDa subunit). |
| Application【应用】 | Anti-CSTF3 (N-terminal) antibody produced in rabbit has been used in chromatin immunoprecipitation and immunoblotting. |
| Biochem/physiol Actions【生化/生理作用】 | Cleavage stimulatory factor (CstF3) is required for proper 3′-end cleavage and is critical for the assembly of the CstF complex, bridging both CSTF1 and CSTF2. CSTF3 also interacts directly with the RNA polymerase II C-terminal domain (CTD), but with lower efficiency than CSTF1. |
| Physical form【外形】 | Solution in 0.01 M phosphate buffered saline, pH 7.4, containing 15 mM sodium azide. |
产品说明
| Storage and Stability【储存及稳定性】 | Store at –20 ℃. For continuous use, the product may be stored at 2–8 ℃ for up to one month. For extended storage, freeze in working aliquots at –20 ℃. Repeated freezing and thawing, or storage in “frost-free” freezers, is not recommended. If slight turbidity occurs upon prolonged storage, clarify the solution by centrifugation before use. Working dilutions should be discarded if not used within 12 hours. |
| Disclaimer【免责声明】 | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
安全信息
| Storage Class Code【储存分类代码】 | 12 - Non Combustible Liquids |
