Anti-DDX5 antibody produced in rabbit

NA.41

Anti-DDX5 Antibody detects endogenous levels of total DDX5 protein.
DDX5 (DEAD, Asp-Glu-Ala-Asp, box helicase 5) is a multifunctional protein belonging to the DEAD box family of RNA helicases. It consists of twelve conserved motifs (including the signature D-E-A-D motif) forming a conserved ′helicase′ central domain, which plays an important role in the RNA metabolism.

The antiserum was produced against synthesized peptide derived from human DDX5/DEAD-box Protein 5.

Immunogen Range: 565-614

Anti-DDX5, C-Terminal antibody produced in rabbit is suitable for indirect immunofluorescence and indirect ELISA.

DDX5 (DEAD, Asp-Glu-Ala-Asp, box helicase 5) is associated with the regulation of pre-mRNA splicing mechanism. It acts as a transcriptional coactivator to control alternative splicing during the formation of spliceosome. DDX5 provides stability to the RNA secondary structure during several activities such as in the translation initiation, nuclear and mitochondrial splicing. It facilitates the unwinding as well as detachment of protein part from RNA. The protein also participates in the estrogen- and androgen-signaling pathway.

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Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

rabbit

100

unconjugated

affinity isolated antibody

primary antibodies

polyclonal

buffered aqueous solution

antigen 69 kDa

rat, mouse, human

~1 mg/mL

ELISA: 1:1000
immunofluorescence: 1:100-1:500

P17844

P17844

wet ice

−20℃

human ... DDX5(1655)

12 - Non Combustible Liquids

nwg