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Anti-EFTUD2 antibody produced in rabbit
产品别名
Anti-EFTUD2 antibody produced in rabbit
U5 snRNP- specific protein
Snrp116
116 kDa U5 small nuclear ribonucleoprotein component
KIAA0031
116 kDa
基本信息
NACRES | NA.41 |
General description【一般描述】 | Anti-EFTUD2 Antibody detects endogenous levels of total EFTUD2 protein. EFTUD2 (Elongation factor Tu GTP binding domain containing 2) is a member of the U5 small nuclear ribonucleoprotein particle (snRNP) located on chromosome region 17q21.31. It encodes a small GTPase (116kDa) component of the major spliceosome. It consists of a GTP-binding domain and several other conserved domains homologous to the translational elongation factor EF-2. Its N-terminal domain has an acidic domain. |
Immunogen【免疫原】 | The antiserum was produced against synthesized peptide derived from human EFTUD2. Immunogen Range: 321-370 |
Application【应用】 | Anti-EFTUD2 antibody produced in rabbit is suitable for immunohistochemistry and western blot. |
Biochem/physiol Actions【生化/生理作用】 | EFTUD2 (Elongation factor Tu GTP binding domain containing 2) acts as a component of the spliceosome complex during translocation of mRNA on the ribosome. It produces mature mRNAs by binding to GTP during the processing of precursor mRNAs. Haploinsufficient genetic mutation in EFTUD2 causes a sporadic malformation syndrome, mandibulofacial dysostosis with microcephaly (MFDM), characterized with severe craniofacial abnormalities, microcephaly, growth delay, hearing loss, cleft palate, choanal atresia and dysmorphic features. |
Features and Benefits【特点和优势】 | Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more. |
Physical form【外形】 | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
产品性质
biological source【生物来源】 | rabbit |
Quality Level【质量水平】 | 100 |
conjugate【偶联物】 | unconjugated |
antibody form【抗体形式】 | affinity isolated antibody |
antibody product type | primary antibodies |
clone【克隆】 | polyclonal |
form【形式】 | buffered aqueous solution |
mol wt【分子量】 | antigen 109 kDa |
species reactivity | human, mouse |
concentration【浓度】 | ~1 mg/mL |
technique(s) | ELISA: 1:40000 immunohistochemistry: 1:50-1:100 western blot: 1:500-1:1000 |
NCBI accession no.【NCBI登记号】 | Q15029 |
UniProt accession no.【UniProt登记号】 | Q15029 |
shipped in【运输】 | wet ice |
storage temp.【储存温度】 | −20℃ |
Gene Information | human ... EFTUD2(9343) |
安全信息
Storage Class Code【储存分类代码】 | 12 - Non Combustible Liquids |
WGK | nwg |