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ANTI-EIF4A3(C-TERMINAL) antibody produced in rabbit
| 产品编号： | 3359600 |
| 规格： | affinity isolated antibody, buffered aqueous solution |
| 包装规格： | 400 μL |
| 产品类别： | 进口试剂 |
| 品牌： | Sigma-Aldrich |
| 优惠价： | 立即咨询 |
产品别名
ANTI-EIF4A3(C-TERMINAL) antibody produced in rabbit
ATP-dependent RNA helicase DDX48
DDX48
EIF4A3
KIAA0111
Eukaryotic initiation factor 4A-III
产品性质
| biological source【生物来源】 | rabbit |
| Quality Level【质量水平】 | 100 |
| antibody form【抗体形式】 | affinity isolated antibody |
| antibody product type | primary antibodies |
| clone【克隆】 | polyclonal |
| form【形式】 | buffered aqueous solution |
| mol wt【分子量】 | 46871 Da |
| species reactivity | human |
| technique(s) | western blot: 1:1000 |
| NCBI accession no.【NCBI登记号】 | NP_055555.1 |
| UniProt accession no.【UniProt登记号】 | P38919 |
| shipped in【运输】 | wet ice |
| storage temp.【储存温度】 | −20℃ |
| Gene Information | human ... EIF4A3(9775) |
基本信息
| General description【一般描述】 | EIF4A3 (Eukaryotic translation initiation factor 4A3) is a chromosome 17q25.3 located gene encoding a DEAD box helicase (eIF4AIII), which is a central component of the exon junction complex (EJC). It belongs to the eukaryotic translation initiation factor 4A family of RNA helicases. |
| Application【应用】 | ANTI-EIF4A3(C-TERMINAL) antibody produced in rabbit is suitable immunohistochemistry (formalin-fixed, paraffin-embedded sections) and western blot applications. |
| Biochem/physiol Actions【生化/生理作用】 | EIF4A3 (Eukaryotic translation initiation factor 4A3) is associated with several activities related to bone morphogenesis including mandible, laryngeal, and limb morphogenesis. It plays a vital role in RNA metabolism and rRNA biogenesis. It is also associated with several downstream process controls including mRNA splicing and nonsense-mediated mRNA decay (NMD). It has been reported that EIF4A3 acts as a RNA clamps or ′place holders′ for holding the attachment of additional factors to RNAs. Missense substitution in EIF4A3 causes a craniofacial disorder, Richieri-Costa-Pereira syndrome characterized with limb defects. |
| Physical form【外形】 | Supplied in PBS with 0.09% (W/V) sodium azide |
产品说明
| Disclaimer【免责声明】 | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
安全信息
| Storage Class Code【储存分类代码】 | 12 - Non Combustible Liquids |
