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Anti-FAP-1 antibody produced in rabbit
产品别名
Anti-FAP-1 antibody produced in rabbit
PTPL1
fibroblast activation protein
DPPIV
PTP1E
PTP-BAS
α subunit
PTPN13
FAPA
SEPRASE
基本信息
| MDL number | MFCD03791521 |
| NACRES | NA.41 |
| General description【一般描述】 | Fibroblast activation protein 1 (FAP-1) is a membrane-associated protein tyrosine phosphatase. It is made up of an ezrin-like cytoskeleton binding domain, six PSD95/Dlg/Z-1 homology (PDZ) domains, and a leucine zipper motif. The FAP-1 gene is located on the human chromosome at 4q21.3. Anti-FAP-1 antibody detects endogenous levels of total FAP-1 protein. |
| Immunogen【免疫原】 | The antiserum was produced against synthesized peptide derived from human FAP-1. Immunogen Range: 331-380 |
| Application【应用】 | Anti-FAP-1 antibody produced in rabbit has been used in western blotting (1: 500) and immunohistochemistry (10 μg/ml). |
| Biochem/physiol Actions【生化/生理作用】 | Fibroblast activation protein 1 (FAP-1) is involved in tumorigenesis, apoptosis, cancer progression, and insulin signaling. It acts as a prognostic marker in high-grade serous ovarian cancer and breast cancer. Overexpression of the FAP-1 gene is associated with several human cancers such as hepatocellular, pancreatic, ovarian, hematological, and colon cancer. Mutations in the FAP-1 gene lead to liver and lung cancer. |
| Features and Benefits【特点和优势】 | Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more. |
| Physical form【外形】 | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
产品性质
| biological source【生物来源】 | rabbit |
| Quality Level【质量水平】 | 100 |
| conjugate【偶联物】 | unconjugated |
| antibody form【抗体形式】 | affinity isolated antibody |
| antibody product type | primary antibodies |
| clone【克隆】 | polyclonal |
| form【形式】 | buffered aqueous solution |
| mol wt【分子量】 | antigen 87 kDa |
| species reactivity | human, mouse, rat |
| concentration【浓度】 | ~1 mg/mL |
| technique(s) | ELISA: 1:10000 immunohistochemistry: 1:50-1:100 western blot: 1:500-1:1000 |
| NCBI accession no.【NCBI登记号】 | Q12884 |
| UniProt accession no.【UniProt登记号】 | Q12884 |
| shipped in【运输】 | wet ice |
| storage temp.【储存温度】 | −20℃ |
| Gene Information | human ... FAP(2191) |
产品说明
| Disclaimer【免责声明】 | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
安全信息
| Storage Class Code【储存分类代码】 | 12 - Non Combustible Liquids |
| WGK | nwg |
