Anti-Frizzled-1 antibody produced in rabbit

MFCD06798442

NA.41

synthetic peptide corresponding to the N-terminal extracellular domain of human frizzled-1, conjugated KLH. The immunizing peptide has 85% homology with the rat and mouse gene.

Anti-Frizzled-1 antibody is suitable for immunohistochemistry studies (formalin-fixed, paraffin-embedded sections) at a concentration of 4μg/mL, using human kidney.

Frizzled homolog protein (FZD) is a seven-pass transmembrane type receptor expressed in various normal tissues such as skeletal muscle, kidney, pancreas, cerebellum and cerebral cortex. In human, ten members (FZD1-FZD10) of Frizzled homolog protein have been identified. Frizzled 1 (FZD1) protein is an essential component of the Wnt/β-catenin pathway. It is expressed in heart, kidney, lung, ovary, pancreas, placenta, and prostate. It has been reported that, FZD1 is up-regulated in several cancers including colon, ovarian, breast neuroblastoma.

Solution in phosphate buffered saline, pH 7.7, containing 0.01% sodium azide.

rabbit

200

unconjugated

affinity isolated antibody

primary antibodies

polyclonal

buffered aqueous solution

human

not available in Japan

immunohistochemistry (formalin-fixed, paraffin-embedded sections): 4 μg/mL using human kidney

Q9UP38

dry ice

−20℃

human ... FZD1(8321)
mouse ... Fzd1(14362)
rat ... Fzd1(58868)

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