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Anti-GA45G antibody produced in rabbit
产品别名
Anti-GA45G antibody produced in rabbit
Cytokine-responsive protein CR6
GADD45G
DDIT-2
Growth arrest and DNA-damage-inducible protein GADD45 γ
DNA-damage-inducible transcript 2
产品性质
| biological source【生物来源】 | rabbit |
| Quality Level【质量水平】 | 100 |
| conjugate【偶联物】 | unconjugated |
| antibody form【抗体形式】 | affinity isolated antibody |
| antibody product type | primary antibodies |
| clone【克隆】 | polyclonal |
| form【形式】 | buffered aqueous solution |
| mol wt【分子量】 | antigen 17 kDa |
| species reactivity | mouse, rat, human |
| concentration【浓度】 | ~1 mg/mL |
| technique(s) | ELISA: 1:1000 immunofluorescence: 1:100-1:500 immunohistochemistry: 1:50-1:100 |
| NCBI accession no.【NCBI登记号】 | O95257 |
| UniProt accession no.【UniProt登记号】 | O95257 |
| shipped in【运输】 | wet ice |
| storage temp.【储存温度】 | −20℃ |
| Gene Information | human ... GADD45G(10912) |
基本信息
| General description【一般描述】 | The GADD45G (growth arrest and DNA damage-inducible gamma) gene is mapped to human chromosome 9q22.2. This gene is highly conserved along evolution. It is found to be localized in various tissues, both in adult and fetus. Anti-GA45G antibody detects endogenous levels of total GA45G protein. |
| Immunogen【免疫原】 | The antiserum was produced against synthesized peptide derived from human GA45G. Immunogen Range: 101-150 |
| Application【应用】 | Anti-GA45G antibody produced in rabbit has been used in western blot analysis. |
| Biochem/physiol Actions【生化/生理作用】 | Growth arrest DNA damage-inducible 45 (GADD45G) has its key role in regulating DNA repair, cell cycle and apoptosis. It regulates cellular action in response to physical and environmental stress. GADD45G is considered as a stress-responsive protein. It controls the functions of proliferating cell nuclear antigen (PCNA), p21, Cdk1 (cyclin-dependent kinase 1), cdc2 (cell division cycle protein 2)/cyclin B1, p38 and c-Jun N-terminal kinase (JNK). GADD45G is associated with the disease progression of diffuse large B-cell lymphoma (DLBL). It is known to be hypermethylated in DLBL. Lowered GADD45G gene expression is observed in solid tumors. |
| Features and Benefits【特点和优势】 | Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more. |
| Physical form【外形】 | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
产品说明
| Disclaimer【免责声明】 | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
安全信息
| Storage Class Code【储存分类代码】 | 12 - Non Combustible Liquids |
| WGK | nwg |
