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Anti-GLP1R antibody produced in rabbit

产品编号:3364987
规格:affinity isolated antibody
包装规格:100 μG
产品类别:进口试剂
品牌:Sigma-Aldrich
优惠价:立即咨询
产品价格
产品编号包装单位单价(元)国内现货国外库存询价单
3364987100 μG5320
产品别名

Anti-GLP1R antibody produced in rabbit

GLP1R

GLP-1R

GLP-1-R

GLP-1 receptor

Glucagon-like peptide 1 receptor

基本信息
NACRES
NA.41
General description【一般描述】
Glucagon-like peptide 1 receptor (GLP1R) protein belongs to the class B G protein-coupled receptor (GPCR) secretin family. This classic seven-transmembrane protein is abundantly expressed in the cardiovascular system. The GLP1R gene is located on the human chromosome 6p21. Anti-GLP1R Antibody detects endogenous levels of total GLP1R protein.
Anti-GLP1R Antibody detects endogenous levels of total GLP1R protein.
Immunogen【免疫原】
The antiserum was produced against synthesized peptide derived from human GLP1R.

Immunogen Range: 101-150
Application【应用】
Anti-GLP1R antibody produced in rabbit has been used in immunofluorescence staining.
Biochem/physiol Actions【生化/生理作用】
Glucagon-like peptide 1 receptor (GLP1R) protein participates in the activation of protein kinase A (PKA), phosphoinositide 3-kinase (PI3K), MEK1/2, and endothelial nitric oxide synthase (eNOS) pathways. Hence, it plays a key role in apoptosis reduction, improved energy metabolism, decreased inflammation in myocardial cells, and vasodilation in myocardial arteries. The large N-terminal extracellular domain of GLP1R participates in ligand binding. Alterations in the GLP1R gene might increase the risk of coronary artery disease (CAD).
Features and Benefits【特点和优势】
Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.
Physical form【外形】
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
产品性质
biological source【生物来源】
rabbit
conjugate【偶联物】
unconjugated
antibody form【抗体形式】
affinity isolated antibody
antibody product type
primary antibodies
clone【克隆】
polyclonal
form【形式】
buffered aqueous solution
mol wt【分子量】
antigen 53 kDa
species reactivity
mouse, human
concentration【浓度】
~1 mg/mL
technique(s)
ELISA: 1:5000
immunofluorescence: 1:100-1:500
NCBI accession no.【NCBI登记号】
P43220
UniProt accession no.【UniProt登记号】
P43220
shipped in【运输】
wet ice
storage temp.【储存温度】
−20℃
Gene Information
human ... GLP1R(2740)
产品说明
Disclaimer【免责声明】
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
安全信息
Storage Class Code【储存分类代码】
12 - Non Combustible Liquids
WGK
nwg
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