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Anti-Glutamate Receptor NMDAR1 (NR1) (Splice Variant Insert C1) antibody produced in rabbit
| 产品编号： | 3365093 |
| 规格： | affinity isolated antibody, lyophilized powder |
| 包装规格： | 25 μG |
| 产品类别： | 进口试剂 |
| 品牌： | Sigma-Aldrich |
| 优惠价： | 立即咨询 |
基本信息
| MDL number | MFCD02096426 |
| NACRES | NA.41 |
| Immunogen【免疫原】 | synthetic peptide representing the sequence of the C1 splice variant. |
| Application【应用】 | Anti-Glutamate Receptor NMDAR1 (NR1) (Splice Variant Insert C1) antibody is suitable for immunohistochemistry (frozen sections) at a dilution of 1:1000-1:2000 and western blot at 1:1000 dilution using rat and mouse tissue. |
| Biochem/physiol Actions【生化/生理作用】 | NMDA receptors (NMDAR) are glutamate-gated ion channels. It is sensitive to N-methyl-D-aspartate (NMDA) and consists of several homologous subunits (NMDAR1). NMDAR is highly expressed in the central nervous system and involved in excitatory synaptic transmission as well as synaptic plasticity. The activity of NMDA receptors are modulated by glycine. It exhibits high calcium permeability and unique voltage-dependent sensitivity to magnesium. It has been reported that phosphorylated NMDA receptors may regulate their function and play a role in many forms of synaptic plasticity such as long-term potentiation. |
| Physical form【外形】 | Lyophilized powder from 5 mM ammonium bicarbonate, so some residual salt may be present |
产品性质
| biological source【生物来源】 | rabbit |
| Quality Level【质量水平】 | 100 |
| conjugate【偶联物】 | unconjugated |
| antibody form【抗体形式】 | affinity isolated antibody |
| antibody product type | primary antibodies |
| clone【克隆】 | polyclonal |
| form【形式】 | lyophilized powder |
| mol wt【分子量】 | antigen 100 kDa |
| species reactivity | rat, mouse |
| packaging【包装】 | antibody small pack of 25 μg |
| technique(s) | immunohistochemistry (frozen sections): 1:1000-1:2000 western blot: 1:1000 using rat and mouse tissue |
| UniProt accession no.【UniProt登记号】 | P35439 |
| storage temp.【储存温度】 | 2-8℃ |
| Gene Information | mouse ... Grin1(14810) rat ... Grin1(24408) |
产品说明
| Disclaimer【免责声明】 | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
安全信息
| Storage Class Code【储存分类代码】 | 13 - Non Combustible Solids |
| WGK | WGK 1 |
