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Anti-GPLD1 antibody produced in mouse
| 产品编号： | 3365617 |
| 规格： | purified immunoglobulin, buffered aqueous solution |
| 包装规格： | 50 μG |
| 产品类别： | 进口试剂 |
| 品牌： | Sigma-Aldrich |
| 优惠价： | 立即咨询 |
产品别名
Anti-GPLD1 antibody produced in mouse
GPIPLDM
GPIPLD
PIGPLD
PIGPLD1
MGC22590
基本信息
| NACRES | NA.41 |
| General description【一般描述】 | Many proteins are tethered to the extracellular face of eukaryotic plasma membranes by a glycosylphosphatidylinositol (GPI) anchor. The GPI-anchor is a glycolipid found on many blood cells. The protein encoded by this gene is a GPI degrading enzyme. Glycosylphosphatidylinositol specific phospholipase D1 hydrolyzes the inositol phosphate linkage in proteins anchored by phosphatidylinositol glycans, thereby releasing the attached protein from the plasma membrane. (provided by RefSeq) |
| Immunogen【免疫原】 | GPLD1 (AAH20748.1, 1 a.a. ~ 176 a.a) full-length human protein. Sequence MSAFRLWPGLLIMLGSLCHRGSPCGLSTHIEIGHRALEFLQLHNGRVNYRELLLEHQDAYQAGIVFPDCFYPSICKGGKFHDVSESTHWTPFLNASVHYIRENYPLPWEKDTEKLVAFLFGITSHMAADVSWHSLGLEQGFLRTMGAIDFHGSYSEAHSAGDFGTVYLHLLNFLVV |
| Application【应用】 | Anti-GPLD1 antibody produced in mouse is suitable for western blot analysis. |
| Biochem/physiol Actions【生化/生理作用】 | GPLD1 (Glycosylphosphatidylinositol specific phospholipase D1) is only expressed in human lver. Inositol phosphate linkage in proteins anchored by phosphatidylinositol-glycans (PI-Gs) is specifically hydrolyzed by GPLD1, suggesting GPLD1 expression might influence the location and expression of PI-G-anchored proteins. Studies have reported that it might be a significant factor in process of leukemia pathogenesis. |
| Physical form【外形】 | Solution in phosphate buffered saline, pH 7.4 |
产品性质
| Quality Level【质量水平】 | 100 |
| biological source【生物来源】 | mouse |
| conjugate【偶联物】 | unconjugated |
| antibody form【抗体形式】 | purified immunoglobulin |
| antibody product type | primary antibodies |
| clone【克隆】 | polyclonal |
| form【形式】 | buffered aqueous solution |
| mol wt【分子量】 | antigen ~19.9 kDa |
| species reactivity | human |
| technique(s) | western blot: 1 μg/mL |
| NCBI accession no.【NCBI登记号】 | BC020748.1 |
| UniProt accession no.【UniProt登记号】 | P80108 |
| shipped in【运输】 | dry ice |
| storage temp.【储存温度】 | −20℃ |
| Gene Information | human ... GPLD1(2822) |
安全信息
| Storage Class Code【储存分类代码】 | 13 - Non Combustible Solids |
| WGK | WGK 1 |
